Study finds four new genetic risk factors for testicular cancer
A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men today. The findings from ...
Genetics
May 12, 2013 |
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Gene associated with adolescent idiopathic scoliosis identified
Researchers from the RIKEN Center for Integrative Medical Sciences in Japan have identified the first gene to be associated with adolescent idiopathic scoliosis (also called AIS) across Asian and Caucasian ...
Genetics
May 12, 2013 |
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Genetic variations associated with susceptibility to bacteria linked to stomach disorders
Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and st ...
Diseases, Conditions, Syndromes
May 07, 2013 |
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Did evolution give us inflammatory disease?
In new research published on March 21, 2013 in the online issue of The American Journal of Human Genetics, researchers from Brigham and Women's Hospital (BWH) demonstrate that some variants in our genes that contribute to a p ...
Genetics
Mar 21, 2013 |
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PCa markers improve predictive performance of existing clinical variables
A genetic score based on PCa risk-associated single nucleotide polymorphisms (SNPs) is an independent predictor of prostate biopsy outcomes, suggest the results of a new study conducted by a group from the Department of Urology ...
Cancer
Mar 18, 2013 |
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Protein implicated in lupus promotes disease progression by distinct mechanisms in different immune cells
Patients with systemic lupus erythematosus (SLE) come under attack by their immune system, producing 'autoantibodies' that inflict damage throughout the body. Antibodies normally target foreign proteins, ...
Immunology
Mar 13, 2013 |
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Signaling pathway linked to fetal alcohol risk: Molecular switch promises new targets for diagnosis, therapy
Fetal alcohol syndrome is the leading preventable cause of developmental disorders in developed countries. And fetal alcohol spectrum disorder (FASD), a range of alcohol-related birth defects that includes fetal alcohol syndrome, ...
Medical research
Feb 20, 2013 |
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Study suggests genetic predisposition to brain injury after preterm birth is sex-specific
In a study to be presented on February 14 at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Francisco, researchers will report that variation in a gene involved in inflammation is ...
Health
Feb 11, 2013 |
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Combining plasma screening methods better identifies diagnostic and therapeutic targets
For the first time, scientists have combined genomic and proteomic analysis of blood plasma to enhance identification of genetically regulated protein traits. This could be applied to any large association study of civilization ...
Genetics
Feb 08, 2013 |
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Calcium-binding protein mutations found in heart rhythm disorders
A team led by Vanderbilt University investigators has discovered two new genes – both coding for the signaling protein calmodulin – associated with severe early-onset disorders of heart rhythm. The findings, reported ...
Cardiology
Feb 06, 2013 |
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Air pollution primes children for asthma-related cockroach allergy
An allergic reaction to cockroaches is a major contributor to asthma in urban children, but new research suggests that the insects are just one part of a more complex story. Very early exposure to certain components of air ...
Immunology
Feb 06, 2013 |
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Researchers uncover gene's role in rheumatoid arthritis, findings pave way for new treatments
University of Michigan research sheds new light on why certain people are more likely to suffer from rheumatoid arthritis – paving the way to explore new treatments for both arthritis and other autoimmune diseases.
Arthritis & Rheumatism
Jan 24, 2013 |
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Genetic CRC risk likely mediated by differential adenoma risk
(HealthDay)—Much of the genetic risk for colorectal cancer (CRC) in the general population is mediated by differential adenoma risk, according to research published in the January issue of Gastroenterology.
Cancer
Jan 10, 2013 |
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All in the family: A genetic link between epilepsy and migraine
New research reveals a shared genetic susceptibility to epilepsy and migraine. Findings published in Epilepsia, a journal of the International League Against Epilepsy (ILAE), indicate that having a strong family history of sei ...
Neuroscience
Jan 07, 2013 |
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Study suggests gene variation may shape bladder cancer treatment
(Medical Xpress)—Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many pancreatic ...
Cancer
Dec 27, 2012 |
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