News tagged with genetic therapy
Scientists identify genetic signatures for aggressive form of prostate cancer
Scientists have discovered two separate genetic 'signatures' for prostate cancer that appear to be able to predict the severity of the disease, leading to hopes that in future, accuracy of prognosis and treatment of the disease ...
Cancer
Oct 08, 2012 |
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Researchers restore children's immune systems with refinements in gene therapy
Researchers have demonstrated that a refined gene therapy approach safely restores the immune systems of some children with severe combined immunodeficiency (SCID). The rare condition blocks the normal development of a newborn's ...
Immunology
Sep 11, 2012 |
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Gene therapy restores sense of smell, may aid research into other diseases caused by cilia defects
Scientists have restored the sense of smell in mice through gene therapy for the first time—a hopeful sign for people who can't smell anything from birth or lose it due to disease.
Medical research
Sep 02, 2012 |
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The path to personalized cancer treatment
In the largest study of its kind, researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. The study is published in Nature on Thursday 29 Mar ...
Cancer
Mar 28, 2012 |
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Scientists find new drug target in breast cancer
Researchers have identified a new protein involved in the development of drug resistance in breast cancer which could be a target for new treatments, they report today in the journal Nature Medicine.
Cancer
May 22, 2011 |
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Discovery helps explain how children develop rare, fatal disease
One of 100,000 children is born with Menkes disease, a genetic disorder that affects the body's ability to properly absorb copper from food and leads to neurodegeneration, seizures, impaired movement, stunted ...
Medical research
Apr 30, 2013 |
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Deficiency in p53 anti-tumor protein delays DNA repair after radiation
Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...
Cancer
Apr 23, 2013 |
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Researchers identify new potential target for cancer therapy
Researchers at UT Southwestern Medical Center have found that alternative splicing – a process that allows a single gene to code for multiple proteins – appears to be a new potential target for anti-telomerase ...
Cancer
Apr 19, 2013 |
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Researchers abuzz over caffeine as cancer-cell killer
(Medical Xpress)—Researchers from the University of Alberta are abuzz after using fruit flies to find new ways of taking advantage of caffeine's lethal effects on cancer cells—results that could one day ...
Cancer
Apr 18, 2013 |
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Gene-expression signature may signify risk for recurrence, metastasis in prostate cancer
A team led by Massachusetts General Hospital (MGH) researchers has identified a genetic signature that appears to reflect the risk of tumor recurrence or spread in men surgically treated for prostate cancer. If confirmed ...
Cancer
Apr 15, 2013 |
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Breast cancer researchers find new drug target companion prognostic test for hormone therapy resistance
A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive ...
Cancer
Apr 01, 2013 |
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Researchers discover brain cancer treatment using genetic material from bone marrow cells
In a first-of-its-kind experiment using microvesicles generated from mesenchymal bone marrow cells (MSCs) to treat cancer, neurological researchers at Henry Ford Hospital have discovered a novel approach for treatment of ...
Cancer
Apr 01, 2013 |
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Fasting time for tumour cells
(Medical Xpress)—Tumours need a steady supply of sufficient nutrients to be able to grow. In order to secure the nutrient availability, they secrete messenger compounds to stimulate neighbouring blood vessels ...
Cancer
Mar 15, 2013 |
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The same genetic defect causes Pompe disease in both humans and dogs
Pompe disease, a severe glycogen storage disease appearing in Lapphunds is caused by a genetic defect in acid α-glucosidase gene. The same genetic mutation also causes the equivalent disease in humans. Based ...
Genetics
Feb 15, 2013 |
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Accelerated biological aging, seen in women with Alzheimer's risk factor, blocked by hormone therapy
Healthy menopausal women carrying a well-known genetic risk factor for Alzheimer's disease showed measurable signs of accelerated biological aging, a new study has found.
Alzheimer's disease & dementia
Feb 13, 2013 |
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