News tagged with hdac

Possible new combination treatment for cancer

Scientists at the Sahlgrenska Academy have developed a new cancer treatment that has proved to be effective in mice. The treatment, which is presented in the prestigious scientific journal PNAS, is based ...

Jun 19, 2014
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Drugs fail to reawaken dormant HIV infection

Scientists at Johns Hopkins report that compounds they hoped would "wake up" dormant reservoirs of HIV inside immune system T cells—a strategy designed to reverse latency and make the cells vulnerable to ...

Mar 23, 2014
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Scientists begin potential HIV cure trials

Scientists and clinicians from five leading UK universities, including King's College London, will begin a groundbreaking trial next year to test a possible cure for HIV infection.

Nov 27, 2013
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Potential new treatments for acute myeloid leukemia

Two separate studies yield key findings for the prevention, diagnosis, treatment and cure for acute myeloid leukemia (AML). AML is a group of heterogeneous diseases with considerable diversity in terms of genetic abnormalities. ...

Nov 25, 2013
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High-dose Vorinostat effective at treating relapsed lymphomas

Patients whose aggressive lymphomas have relapsed or failed to respond to the current front-line chemotherapy regimen now have an effective second line of attack against their disease. Reporting the results of a first-of-its-kind ...

Feb 04, 2013
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Scientists find Achilles' heel of cancer cells

Several substances inhibiting so-called HDAC enzymes have been studied in trials searching for new anti-cancer drugs in recent years. "Trials have shown that HDAC inhibitors are very effective in arresting growth of cultured ...

Nov 05, 2012
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Drug may slow spread of deadly eye cancer

A drug commonly used to treat seizures appears to make eye tumors less likely to grow if they spread to other parts of the body, according to researchers at Washington University School of Medicine in St. ...

Nov 28, 2011
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Tamoxifen resistance -- and how to defeat it

In the last three decades, thousands of women with breast cancer have taken the drug tamoxifen, only to discover that the therapy doesn't work, either because their tumors do not respond to the treatment at all, or because ...

Nov 13, 2011
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