Genetics

Scientists narrow down pool of potential height genes

When it comes to height, our fate is sealed along with our growth plates—cartilage near the ends of bones that hardens as a child develops. Research published April 14 in the journal Cell Genomics shows that cells in these ...

Gastroenterology

Two-organ chip developed to answer fatty liver questions

A new chip that holds different cell types in tiny, interconnected chambers could allow scientists to better understand the physiological and disease interactions between organs. The integrated-gut-liver-on-a-chip (iGLC) ...

Oncology & Cancer

Researchers identify key source of T cell 'exhaustion'

Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited ...

Oncology & Cancer

How genome doubling helps cancer develop

A single cell contains 2-3 meters of DNA, meaning that the only way to store it is to package it into tight coils. The solution is chromatin: a complex of DNA wrapped around proteins called histones. In the 3D space, this ...

Genetics

Genetic links between migraine and blood sugar levels confirmed

In a study published in Human Genetics, QUT Professor Dale Nyholt and QUT Ph.D. researcher Rafiqul Islam, describe using large-scale genome-wide associations studies (GWAS) summary statistics to analyze hundreds of thousands ...

Genetics

A human interactome to prioritize drug discovery

Scientists at Open Targets, EMBL's European Bioinformatics Institute (EMBL-EBI), and GSK are revealing the shared basis of diseases using a map of interacting human proteins. By helping to understand how biological processes ...

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