News tagged with human genome project
(Medical Xpress)—How does San Francisco Giants slugger Pablo Sandoval swat a 95 mph fastball, or tennis icon Venus Williams see the oncoming ball, let alone return her sister Serena's 120 mph serves? For ...
Neuroscience May 08, 2013 | 3.2 / 5 (6) | 0 |
(Medical Xpress)—Cracking the DNA code for a complex region of the human genome has helped 14 North American scientists, including five at Simon Fraser University, chart new territory in immunity research.
Genetics Apr 17, 2013 | 5 / 5 (2) | 0 |
A decade after completion of the Human Genome Project on April 14, 2003, a top official of the National Institutes of Health surveyed the rarefied view from that mountaintop:
Genetics Apr 15, 2013 | not rated yet | 0
(HealthDay)—As scientists mark the 10th anniversary Sunday of the completion of the Human Genome Project, they will note how that watershed effort has led to the discovery of the genetic underpinnings of ...
Genetics Apr 12, 2013 | 4.5 / 5 (2) | 1 |
Tumor suppression, the family business of the sibling genes p53, p63 and p73, is undermined from within by the split personalities of p63 and p73, which each produce protein forms that not only block the work of the other ...
Cancer Apr 08, 2013 | not rated yet | 0
President Barack Obama on Tuesday proposed an effort to map the brain's activity in unprecedented detail, as a step toward finding better ways to treat such conditions as Alzheimer's, autism, stroke and traumatic ...
Neuroscience Apr 02, 2013 | 5 / 5 (5) | 0
UConn researchers are at the forefront of new discoveries and understanding about the smallest molecules in the body that can have a momentous impact on human health.
Genetics Mar 26, 2013 | not rated yet | 0
(Medical Xpress)—The ambitious and controversial Brain Activity Map (BAM), initiative instituted by a small group of researchers last year, has been steadily gaining momentum. Earlier this week, a proof ...
Neuroscience Mar 22, 2013 | 5 / 5 (5) | 1 |
Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction ...
Medical research Mar 03, 2013 | 3.8 / 5 (5) | 4 |
Researchers have identified a microRNA liver gene, miR-27b, which regulates lipid (cholesterol or fat) levels in the blood. This regulator gene controls multiple genes involved in dyslipidemia—abnormal blood cholesterol ...
Genetics Feb 07, 2013 | not rated yet | 0
Biobanks are organizations that collect, store and share human specimens (e.g., blood, solid tissues, hair) for research purposes. The rise of the human genome project and of large-scale genetics studies ...
Genetics Jan 28, 2013 | not rated yet | 0
Almost 10 years after completion of the Human Genome Project in 2003, scientists are making progress toward the next major goal in applying the genetic information in that "Book of Life" in medicine, leaders of an international ...
Genetics Jan 23, 2013 | not rated yet | 0
The Personal Genome Project Canada (PGP-C) launches this week giving Canadians an unprecedented opportunity to participate in a groundbreaking research study about human genetics and health.
Genetics Dec 10, 2012 | not rated yet | 0
Researchers produce a catalog of the deleterious and disease-causing genetic variants in healthy people
Researchers at Cambridge and Cardiff have found that, on average, a normal healthy person carries approximately 400 potentially damaging DNA variants and two variants known to be associated directly with disease traits. They ...
Genetics Dec 06, 2012 | not rated yet | 0 |
(Medical Xpress)—Each year, more and more pieces of the human genome puzzle fall into place, but large holes still remain. Researchers at the University of Wisconsin-Madison hope to fill in many more pieces ...
Genetics Oct 03, 2012 | 5 / 5 (1) | 0
Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with a primary goal to determine the sequence of chemical base pairs which make up DNA and to identify and map the approximately 20,000-25,000 genes of the human genome from both a physical and functional standpoint.
The project began in 1990 initially headed by James D. Watson at the U.S. National Institutes of Health. A working draft of the genome was released in 2000 and a complete one in 2003, with further analysis still being published. A parallel project was conducted outside of government by the Celera Corporation. Most of the government-sponsored sequencing was performed in universities and research centers from the United States, Canada, New Zealand and Britain. The mapping of human genes is an important step in the development of medicines and other aspects of health care.
While the objective of the Human Genome Project is to understand the genetic makeup of the human species, the project also has focused on several other nonhuman organisms such as E. coli, the fruit fly, and the laboratory mouse. It remains one of the largest single investigational projects in modern science.
The HGP originally aimed to map the nucleotides contained in a haploid reference human genome (more than three billion). Several groups have announced efforts to extend this to diploid human genomes including the International HapMap Project, Applied Biosystems, Perlegen, Illumina, JCVI, Personal Genome Project, and Roche-454.
The "genome" of any given individual (except for identical twins and cloned organisms) is unique; mapping "the human genome" involves sequencing multiple variations of each gene. The project did not study the entire DNA found in human cells; some heterochromatic areas (about 8% of the total) remain un-sequenced.
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