Diseases, Conditions, Syndromes

Scientists advance understanding of herpesvirus infection

Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle ...

Medical research

Cytomegalovirus hijacks human enzyme for replication

More than 60 percent of the world's population is infected with a type of herpes virus called human cytomegalovirus. The virus replicates by commandeering the host cell's metabolism but the details of this maneuver are unclear.

Medications

FDA approves sylvant for multicentric castleman's disease

(HealthDay)—The U.S. Food and Drug Administration has approved Sylvant (siltuximab) to treat patients with multicentric Castleman's disease (MCD), according to a news release issued by the agency today.

Medical research

Using nanocapsules to deliver vaccines to lungs

Many viruses and bacteria infect humans through mucosal surfaces, such as those in the lungs, gastrointestinal tract and reproductive tract. To help fight these pathogens, scientists are working on vaccines that can establish ...

Medical research

Pressurized virus blasts its infectious DNA into human cells

The virus that causes those painful lip blisters known as cold sores has an internal pressure eight times higher than a car tire, and uses it to literally blast its infectious DNA into human cells, scientists are reporting ...

Immunology

Herpes virus exploits immune response to bolster infection

Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an ...

Genetics

Researchers create map of 'shortcuts' between all human genes

Some diseases are caused by single gene mutations. Current techniques for identifying the disease-causing gene in a patient produce hundreds of potential gene candidates, making it difficult for scientists to pinpoint the ...

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