Researchers from the Perelman School of Medicine at the University of Pennsylvania have developed a vaccine to protect against genital herpes. Tested on both mice and guinea pigs, the immunization led to "mostly sterilizing ...
Sep 20, 2019
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No matter the pathogen—virus, bacterium or fungus—many "pick a specific type of lock" on the surface of cells, which allows the microbe to break and enter into the inner sanctum of the host's genome.
Human herpes virus, commonly known as herpes simplex virus 1 and 2 (HSV-1 and HSV-2), is like that friend who ends up crashing on your couch and never leaves.
Jul 31, 2013
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Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle ...
Apr 12, 2017
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After herpesviruses infect a cell, their genomes are assembled into specialized protein structures called nucelosomes. Many cellular enzyme complexes can modulate these structures to either promote or inhibit the progression ...
Aug 15, 2017
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Circumcision drastically alters the microbiome of the penis, changes that could explain why circumcision offers protection against HIV and other viral infections. In a study to be published on April 16 in mBio, the online ...
Apr 16, 2013
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The cornea—the transparent protective outer layer of the eye critical to helping us see—produces a delicate and limited immune response to fight infections without damaging our vision, according to a new study from the ...
May 24, 2022
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Some diseases are caused by single gene mutations. Current techniques for identifying the disease-causing gene in a patient produce hundreds of potential gene candidates, making it difficult for scientists to pinpoint the ...
Mar 18, 2013
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Saint Louis University research findings published in the December issue of Antimicrobial Agents and Chemotherapy report a family of molecules known as nucleotidyltransferase superfamily (NTS) enzyme inhibitors are promising ...
Dec 18, 2014
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The virus that causes those painful lip blisters known as cold sores has an internal pressure eight times higher than a car tire, and uses it to literally blast its infectious DNA into human cells, scientists are reporting ...
Jul 24, 2013
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