Diseases, Conditions, Syndromes

Discovery suggests new route to fight infection, disease

New research reveals how a single protein interferes with the immune system when exposed to the bacterium that causes Legionnaires' disease, findings that could have broad implications for development of medicines to fight ...

Diseases, Conditions, Syndromes

Synthetic molecule 'kicks and kills' some persistent HIV in mice

Scientists have designed a synthetic molecule that can reactivate dormant human immunodeficiency virus (HIV) in mice and lead to the death of some of the infected cells, according to a study published in PLOS Pathogens.

Genetics

New technique searches 'dark genome' for disease mutations

When doctors can't find a diagnosis for patient's disease, they turn to genetic detectives. Equipped with genomic sequencing technologies available for less than 10 years, these sleuths now routinely search through a patient's ...

Immunology

How the human body first fights off pathogens

People constantly encounter viruses, bacteria or parasites. Fortunately, our skin, the specialized lining of our guts and other parts of our body that are exposed to the outside world prevent them from entering. When a pathogen ...

Diseases, Conditions, Syndromes

Parasite protein could help inform new anti-tuberculosis strategies

Proteins produced by the parasite that causes toxoplasmosis may be involved in immune system processes that can help fight mycobacteria, according to a new study. The findings, published in PLOS Pathogens, suggest that these ...

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