Scientists have discovered how mutations in DNA can cause neurodegenerative disease. The discovery is an important step towards better treatment to slow the progression or delay onset in a range of incurable diseases such ...
May 13, 2019
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Johns Hopkins researchers have identified a natural mechanism that might one day be used to block the expression of the mutated gene known to cause Huntington’s disease. Their experiments offer not an immediate cure, ...
Jun 23, 2011
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By adjusting the levels of a key signaling protein, researchers improved motor function and brain abnormalities in experimental animals with a form of Huntington's disease, a severe neurodegenerative disorder. The new findings ...
Jan 5, 2015
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A team of researchers at the UC Davis Institute for Regenerative Cures has developed a technique for using stem cells to deliver therapy that specifically targets the genetic abnormality found in Huntington's disease, a hereditary ...
Jan 19, 2012
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While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other ...
Feb 15, 2022
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Huntington's disease is the most common neurodegenerative disorder controlled by a single gene and is characterized by motor and cognitive deficits and psychiatric symptoms. Currently, no treatments can stop or reverse the ...
Oct 13, 2023
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The drug valbenazine statistically improves chorea, a movement disorder commonly associated with Huntington's disease, when compared to a placebo, according to a recent international study led by UTHealth Houston researcher ...
May 19, 2023
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Huntington's disease is a progressively debilitating brain disease that causes uncontrolled movements, psychological problems, and loss of cognition. Huntington's is caused by a mutation in the gene that encodes huntingtin, ...
Nov 12, 2021
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Creating induced pluripotent stem cells or iPS cells allows researchers to establish "disease in a dish" models of conditions ranging from Alzheimer's disease to diabetes. Scientists at Yerkes National Primate Research Center ...
Sep 5, 2014
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Cambridge scientists have shown how the brain's ability to clear out toxic proteins is impaired in Huntington's disease and other forms of dementia—and how, in a study in mice, a repurposed HIV drug was able to restore ...
Apr 26, 2023
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