Whole exome sequencing revealed that colorectal cancers with high mutational load (MSI-H) predominantly use "immunoediting" to escape immune surveillance while colorectal cancers with low mutational load (MSS) use oncogenic ...
Oct 30, 2017
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(HealthDay)—The interface between allergic responses and oncology is being explored, which may have implications for treatment, according to a European Academy of Allergy and Clinical Immunology position paper published ...
Jan 5, 2017
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A fundamental metabolic shift in immune system cells has been identified by A*STAR researchers as responsible for whether they attack or tolerate disease recognized by our immune defenses. If the cells do not respond correctly, ...
Sep 25, 2015
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Ripping a page from the Star Trek script, specialized cells of the barrier that lines the inside of the intestines and airways of humans have invoked a biological version of Captain Kirk's famous command "shields up" as a ...
Jul 7, 2014
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A Ludwig Cancer Research study suggests that the clinical efficacy of checkpoint blockade, a powerful new strategy to harness the immune response to treat cancers, might be dramatically improved if combined with oncolytic ...
Mar 5, 2014
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Immune cells undergo 'spontaneous' changes on a daily basis that could lead to cancers if not for the diligent surveillance of our immune system, Melbourne scientists have found.
Feb 2, 2014
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(Medical Xpress)—Patients suffering from leukaemia could have their immune system engineered to fight the disease, after scientists at the University of Birmingham discovered that they lacked an immune response to a certain ...
Sep 20, 2013
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A new finding could lead to novel treatments to reduce bleeding in trauma and severe infections. The research, from Oklahoma Medical Research Foundation scientists Lijun Xia, M.D., Ph.D., Jianxin Fu, M.D., Ph.D., and Brett ...
Sep 1, 2013
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Researchers from the Perelman School of Medicine at the University of Pennsylvania demonstrate for the first time that the immune system influences the skin microbiome. A new study found that the skin microbiome – a collection ...
Aug 26, 2013
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A team of international researchers from Duke-NUS Graduate Medical School Singapore and the Johns Hopkins University School of Medicine (USA) has identified a self-perpetuating signaling circuit inside connective tissue cells ...
Jul 16, 2013
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