Parkinson's & Movement disorders

Research uncovers how pesticides increase risk for Parkinson's disease

Previous studies have shown the certain pesticides can increase the risk for developing Parkinson's disease. Now, UCLA researchers have now found that the strength of that risk depends on an individual's genetic makeup, which ...

Inflammatory disorders

Targeting necroptosis for inflammatory myopathies

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has ...

Neuroscience

On the ups and downs of the seemingly idle brain

Even in its quietest moments, the brain is never "off." Instead, while under anesthesia, during slow-wave sleep, or even amid calm wakefulness, the brain's cortex maintains a cycle of activity and quiet called "up" and "down" ...

Cardiology

30-day results of ADAPT-DES registry reported at TCT 2011

The relationship of platelet responsiveness to antiplatelet medications; and, the correlation of poor response, and overall platelet aggregation while on dual antiplatelet therapy to the risk of drug-eluting stent thrombosis ...

Neuroscience

Monkey gaze study shows dopamine's role in response inhibition

University of Tsukuba researchers report the importance of the brain's dopaminergic system for inhibiting already-planned actions. They trained monkeys to redirect their gaze toward targets presented on a screen, apart from ...

Oncology & Cancer

Preventing cancer development inside the cell cycle

Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells. The ...

Immunology

A switch for autoimmunity

When a virus or bacteria comes calling, protein "sensors" in your cells can detect the invader's DNA and activate inflammatory responses to prevent infection. One such sensor is cGAS (cyclic GMP-AMP synthase).

Medical research

Metabolic response behind reduced cancer cell growth

Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma. The reduction is caused by changes in the cancer cells' ...

Immunology

How immune cells move against invaders

UCSF scientists have discovered the unexpected way in which a key cell of the immune system prepares for battle. The finding, they said, offers insight into the processes that take place within these cells and could lead ...

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