Health
Is it okay to take antidepressants while pregnant?
Mental health conditions including anxiety and depression are among the most common disorders affecting women during pregnancy and after birth.
Dec 18, 2023
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News tagged with inhibitors
Oncology & Cancer
Researchers develop 'potent and specific' compounds to curb cancer growth
Proteasomes are protein-degrading complexes that are important for cancer cell survival. Proteasome inhibitors are commonly used to treat diseases such as multiple myeloma and mantle cell lymphoma. Proteasomes have three ...
Dec 14, 2023
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Oncology & Cancer
Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers
A new study, published online ahead of print in Journal for ImmunoTherapy of Cancer on December 6, has identified a novel biomarker for ICIs in human cancers.
Dec 13, 2023
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Diabetes
Prenatal exposure to GLP-1 receptor agonists and other second-line antidiabetics may not pose greater risk than insulin
Infants born to women with pre-gestational type 2 diabetes who take second-line non-insulin antidiabetic medications (ADMs) during pregnancy are at no higher risk of major congenital malformations (MCMs) than infants born ...
Dec 11, 2023
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Oncology & Cancer
Long-term results show combination treatment that skips chemotherapy is effective for older patients with Ph+ ALL
Older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who were not good candidates for the standard treatment of intensive chemotherapy had a median overall survival (OS) of 6.5 years ...
Dec 11, 2023
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Oncology & Cancer
Potentially targetable fusion RNAs may be more common in metastatic breast cancer than previously realized
Comprehensive profiling of fusion RNAs present in a large cohort of metastatic breast tumors revealed unique fusion mutations that may be therapeutically targetable, according to results presented at the San Antonio Breast ...
Dec 8, 2023
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Medications
How drugs can target the thick 'scar tissue' of pancreatic cancer
Pancreatic cancer is one of the deadliest cancers—only about one in eight patients survives five years after diagnosis. Those dismal statistics are in part due to the thick, nearly impenetrable wall of fibrosis, or scar ...
Dec 6, 2023
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Oncology & Cancer
Blood hormone levels identify which post-menopausal women will benefit most from a medication to prevent breast cancer
Research led by Queen Mary University of London's Wolfson Institute of Population Health has found that hormone levels, measured through blood tests, are an important indicator of whether women will benefit from recently ...
Dec 6, 2023
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Oncology & Cancer
Model uses sociodemographic factors to predict aromatase inhibitor non-adherence risk
A new risk model uses baseline sociodemographic and financial measures to predict which patients prescribed long-term therapy with aromatase inhibitors for breast cancer are at significantly higher risk of stopping that therapy ...
Dec 6, 2023
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Medications
CVD mortality similar with diuretic, ACE inhibitor, or calcium channel blocker
For patients with hypertension and at least one other coronary heart disease risk factor, cardiovascular disease (CVD) mortality is similar for those receiving a thiazide-type diuretic, calcium channel blocker (CCB), or angiotensin-converting ...
Dec 4, 2023
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