Diabetes

Study may point to new ways to reverse insulin resistance

Researchers at Vanderbilt University have discovered how insulin crosses the capillary endothelium to exit blood vessels and stimulate skeletal muscle cells—a major finding that may lead to new ways to reverse insulin resistance, ...

Diabetes

Type 2 diabetes has hepatic origins

Affecting as many as 650 million people worldwide, obesity has become one of the most serious global health issues. Among its detrimental effects, it increases the risk of developing metabolic conditions, and primarily type ...

Alzheimer's disease & dementia

Dolphin brains show signs of Alzheimer's Disease

Study suggests Alzheimer's disease and Type 2 diabetes might both be the price of a longer lifespan, with altered insulin function the common cause.

Medical research

Our muscles measure the time of day

Biological clocks throughout the body trigger the release of the hormone melatonin during sleep, induce the secretion of digestive enzymes at lunchtime or keep us awake at the busiest moments of the day. A "master clock" ...

Medical research

Heart hormones protect against obesity and insulin resistance

Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) in Lake Nona, Florida have shown that enhanced natriuretic peptide (NP) signaling in adipose tissue protects against obesity and insulin resistance. ...

Immunology

When liver immune cells turn bad

A high-fat diet and obesity turn "hero" virus-fighting liver immune cells "rogue", leading to insulin resistance, a condition that often results in type 2 diabetes, according to research published today in Science Immunology.

Alzheimer's disease & dementia

Insulin resistance may lead to faster cognitive decline

A new Tel Aviv University study published in the Journal of Alzheimer's Disease finds that insulin resistance, caused in part by obesity and physical inactivity, is also linked to a more rapid decline in cognitive performance. ...

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