Diabetes

Why do people with diabetes develop severe COVID-19?

Throughout the COVID-19 pandemic, clinicians have noted that certain patients are at especially high risk of developing severe illness or dying from coronavirus infection. Type 2 diabetes—a condition affecting more than ...

Diseases, Conditions, Syndromes

Why do some people get severe COVID-19? The nose may know

The body's first encounter with SARS-CoV-2, the virus behind COVID-19, happens in the nose and throat, or nasopharynx. A new study in the journal Cell suggests that the first responses in this battleground help determine ...

Immunology

Exercising muscle combats chronic inflammation on its own

Biomedical engineers at Duke University have demonstrated that human muscle has an innate ability to ward off the damaging effects of chronic inflammation when exercised. The discovery was made possible through the use of ...

Diseases, Conditions, Syndromes

Type III interferons: Protective or harmful in COVID-19?

Interferons and other cytokines produced by the immune system are important defenses against viral infections, but as we have seen in COVID-19, they can also contribute to damaging, potentially life-threatening lung inflammation. ...

Immunology

How a fat cell's immune response makes obesity worse

When obesity occurs, a person's own fat cells can set off a complex inflammatory chain reaction that can further disrupt metabolism and weaken immune response—potentially placing people at higher risk of poor outcomes from ...

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