Some of you may have made a New Year's resolution to hit the gym to tackle that annoying belly fat. But have you ever wondered how physical activity produces this desired effect? A signaling molecule called interleukin-6 ...
Dec 27, 2018
0
8019
Researchers at the University of Gothenburg, Sweden, have clarified the link between the molecule interleukin-6 (IL-6) in the brain and obesity. In experiments on rats and mice, they show that the molecule does affect the ...
May 3, 2019
0
44
(Medical Xpress)—A team of researchers affiliated with several institutions in the U.K. has found that nine-year-old children with high levels of serum interleukin-6 (IL-6) in their blood have a higher-than-average risk ...
Highly elevated platelet levels fuel tumor growth and reduce the survival of ovarian cancer patients, an international team of researchers led by scientists at The University of Texas MD Anderson Cancer center reports in ...
Feb 15, 2012
0
0
By digging a little deeper, researchers may have found a potential target for reversing the deadly blood infection sepsis.
Jun 10, 2011
0
0
Studying the expression of genes that are dependent on vitamin D makes it possible to identify individuals who will benefit from vitamin D supplementation, shows a University of Eastern Finland study published recently in ...
Aug 13, 2013
0
0
A team of Russian scientists has identified the role of the interleukin-6 molecule in the development of allergic asthma. It may comprise a new target for the treatment of this disease. The results are published in Frontiers ...
Dec 18, 2018
0
1
A number of different immunological mechanisms ensure the successful establishment and maintenance of pregnancy. Imbalance in these mechanisms is associated with adverse pregnancy outcomes. In a review published in Advances ...
Jan 10, 2012
0
0
(HealthDay)—Being both neurotic and conscientious may be good for your health.
Nov 24, 2012
0
0
A potential new treatment for type 2 diabetes has multiple, positive effects on health and metabolism in mice, reports a study in Nature. The new drug might have potential for treating a variety of disorders in addition to ...
Sep 26, 2019
0
4
More reference expression data
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. In terms of host response to a foreign pathogen, IL-6 has been shown, in mice, to be required for resistance against the bacterium, Streptococcus pneumoniae. IL-6 is also a "myokine," a cytokine produced from muscle, and is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. During exercise, it is thought to act in a hormone-like manner to mobilize extracellular substrates and/or augment substrate delivery (Petersen, J Appl Physiol 2005). Additionally, osteoblasts secrete IL-6 to stimulate osteoblast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10.
This text uses material from Wikipedia, licensed under CC BY-SA
