Western diet changes gut bacteria and triggers colitis in those at risk
Certain saturated fats that are common in the modern Western diet can initiate a chain of events leading to complex immune disorders such as inflammatory bowel diseases (IBD) in people with a genetic predisposition, according ...
Medical research
Jun 13, 2012 |
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Researchers identify potential new HIV vaccine/therapy target
After being infected with simian immunodeficiency virus (SIV) in a laboratory study, rhesus macaques that had more of a certain type of immune cell in their gut than others had much lower levels of the virus in their blood, ...
HIV & AIDS
May 30, 2012 |
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Exhaustion renders immune cells less effective in cancer treatment
Rather than stimulating immune cells to more effectively battle cancerous tumors, treatment with the protein interleukin-12 (IL-12) has the opposite effect, driving these intracellular fighters to exhaustion, a Mayo Clinic ...
Immunology
May 09, 2012 |
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Study finds 'Western diet' detrimental to fetal hippocampal tissue transplants
Researchers interested in determining the direct effects of a high saturated fat and high cholesterol (HFHC) diet on implanted fetal hippocampal tissues have found that in middle-aged laboratory rats the HFHC diet elevated ...
Medical research
Apr 23, 2012 |
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Colitis in test mice responds to treatment with human umbilical cord-derived mensenchymal cells
When laboratory mice were modeled with colitis and treated with human umbilical cord-derived mesenchymal cells, the cells homed in on the inflamed colon and effectively ameliorated colitis, reported a study published in a ...
Medical research
Apr 23, 2012 |
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IL-32 expression upregulated in chronic rhinosinusitis
(HealthDay) -- Interleukin-32 (IL-32) mRNA expression is significantly higher in biopsies obtained from patients with chronic rhinosinusitis (CRS), compared to levels found in biopsies obtained from individuals ...
Inflammatory disorders
Apr 17, 2012 |
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Immunotherapy and chemotherapy regimen may prolong survival in advanced cancers
Maintenance therapy with interleukin-2 and 13-cis retinoic acid may be an inexpensive method for increasing survival in patients with a variety of stage 4 cancers, according to data reported at the AACR Annual Meeting 2012, ...
Cancer
Apr 03, 2012 |
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Biomarker identified in relation to drug response in refractory urothelial cancer
The antiangiogenic drug pazopanib has demonstrated clinically meaningful activity in patients with refractory urothelial cancer, according to results presented at the AACR Annual Meeting 2012, held here March 31 - April 4. ...
Cancer
Apr 01, 2012 |
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Two experimental drugs could improve psoriasis treatment
(HealthDay) -- A new type of treatment may be on the horizon for people with moderate to severe cases of the chronic skin condition known as psoriasis.
Immunology
Mar 28, 2012 |
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Researchers identify new regulator in allergic diseases
Researchers have taken a critical step in understanding how allergic reactions occur after identifying a genetic signature for regulation of a key immune hormone, interleukin (IL-13).
Immunology
Mar 28, 2012 |
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Dual mode laser therapy effectively treats acne vulgaris
(HealthDay) -- A series of Nd:YAG laser treatments effectively and rapidly reduces both inflammatory and noninflammatory acne vulgaris lesions, according to a study published in the April issue of the Journal of ...
Diseases, Conditions, Syndromes
Mar 27, 2012 |
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Scientists identify novel pathway for T-cell activation in leprosy
UCLA researchers pinpointed a new mechanism that potently activates T-cells, the group of white blood cells that play a major role in fighting infections.
Medical research
Mar 25, 2012 |
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How music prevents heart transplant rejection
Music has a fundamental affect on humans. It can reduce stress, enhance relaxation, provide a distraction from pain, and improve the results of clinical therapy. New research published in BioMed Central's open access journal ...
Cardiology
Mar 22, 2012 |
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Scientists boost potency, reduce side effects of IL-2 protein used to treat cancer
The utility of a naturally occurring protein given, sometimes to great effect, as a drug to treat advanced cancers is limited by the severe side effects it sometimes causes. But a Stanford University School of Medicine scientist ...
Medical research
Mar 18, 2012 |
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Genetic studies lay the foundations for anti-inflammatory drugs to prevent heart disease
Two large international meta-analyses published Online First in The Lancet provide compelling new evidence that interleukin-6 receptor (IL6R), a protein involved in inflammatory signaling, has a causal role in the develo ...
Cardiology
Mar 13, 2012 |
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