Diseases, Conditions, Syndromes

A promising target for kidney fibrosis

When the kidneys - vital organs for filtering the body's entire blood supply - become injured, it can set in motion an unfortunate chain of events that leads to a decline in health. Sometimes, in response to chronic injury, ...

Diseases, Conditions, Syndromes

Kidney fibrosis in older transplants links to failure

Clinically, kidney fibrosis can be used to assess stage, progression, and prognosis for both kidney transplants and kidney disease. There is debate as to whether kidney fibrosis is a maladaptive, injury-triggered process ...

Diseases, Conditions, Syndromes

Identification of a driver of fibrosis in chronic kidney disease

Chronic kidney disease can develop in response to a variety of insults and is characterized by progressive renal fibrosis and atrophy of kidney tubule. Therapeutic options are limited and the disease is often not detected ...

Diseases, Conditions, Syndromes

Potential new therapy approaches to reverse kidney damage identified

Adults who are worried or terrified sometimes curl up into a fetal position. Likewise, adult cells that are injured, including genetic injury leading to cancer, initiate a process that was present during embryonic development.

Diseases, Conditions, Syndromes

Researchers identify potential new targets for treating kidney disease

Chronic diseases such as diabetes and hypertension cause injury to the kidneys, which can lead to scarring and the development of chronic kidney disease. By identifying proteins important to this scarring process, researchers ...

page 3 from 6