Oncology & Cancer

Denosumab reduces burden of giant-cell tumor of the bone

Treatment with denosumab, a drug targeted against a protein that helps promote bone destruction, decreased the number of tumor giant cells in patients with giant-cell tumor of the bone, and increased new bone formation, according ...

Parkinson's & Movement disorders

Drug homing method helps rethink Parkinson's

The brain is the body's most complex organ, and consequently the least understood. In fact, researchers like Michael Tadross, MD, PhD, wonder if the current research methods employed by neuroscientists are telling us as much ...

Medical research

Plague alters cell death to kill host

Northwestern Medicine scientists are continuing to unravel the molecular changes that underlie one of the world's deadliest and most infamous respiratory infections.

Medical research

Study identifies potential new pathway for drug development

A newly found understanding of receptor signaling may have revealed a better way to design drugs. A study from Nationwide Children's Hospital suggests that a newly identified group of proteins, alpha arrestins, may play a ...

Immunology

Jump-starting cheaper cancer vaccines

Dendritic cells (DCs)—workhorses of the immune system—derived from human embryonic stem cells (hESCs) may provide an economical way of generating off-the-shelf therapeutic vaccines against cancers, according to research ...

Medical research

Finding a family for a pair of orphan receptors in the brain

Researchers at Emory University have identified a protein that stimulates a pair of "orphan receptors" found in the brain, solving a long-standing biological puzzle and possibly leading to future treatments for neurological ...

Medical research

Researchers study novel drug-delivery system

University of Mississippi School of Pharmacy researchers are studying an improved method for delivering drugs that treat pain and inflammation.

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