Taming physical forces that block cancer treatment
A Massachusetts General Hospital research team has identified factors that contribute to solid stress within tumors, suggesting possible ways to alleviate it, and has developed a simple way to measure such pressures.
Cancer
Sep 20, 2012 |
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Lymphatic fluid takes detour
When tumours metastasise, they can block lymphatic vessels, as researchers from ETH Zurich have discovered using a new method. The lymphatic fluid subsequently has to find a new path through the tissue. Such ...
Medical research
May 20, 2013 |
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Tumor-activated protein promotes cancer spread
Researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center report that cancers physically alter cells in the lymphatic system – a network of vessels that transports and ...
Cancer
May 13, 2013 |
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New study confirms immune cells are guided by gradients
(Medical Xpress)—A group of researchers in Austria and Switzerland has for the first time proven that immune cells migrate along chemical concentration gradients. This process has long been assumed but ...
Immunology
Jan 18, 2013 |
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Blood test accurately detects lymphedema, study shows
Scientists at the Stanford University School of Medicine have identified a set of proteins circulating in blood whose levels accurately flag the presence of lymphedema. The findings, to be reported Dec. 18 in PLoS ONE, spur o ...
Inflammatory disorders
Dec 18, 2012 |
4.8 / 5 (5) |
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Researchers discover how melanoma cells circumvent the immune system
Melanoma is so dangerous because it tends to metastasize early on. New treatment approaches utilize, among other things, the ability of the immune defense to search out and destroy malignant cells. Yet this strategy is often ...
Cancer
Oct 10, 2012 |
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New mouse model of debilitating lung disease suggests potential treatment regimen
LAM, short for pulmonary lymphangioleiomyomatosis, affects about 1 in 10,000 women of childbearing age and is characterized by proliferation of smooth muscle-like cells in the lung, destruction of lung tissue, and growth ...
Medical research
Oct 03, 2012 |
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Study: Statins may stem tumor growth
(Medical Xpress)—One of the world's top selling drugs potentially also acts against the growth of new lymphatic vessels, with potential implications for cancer therapy. This surprising finding was brought ...
Cancer
Sep 04, 2012 |
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RNA regulator of melanoma could be a new target for cancer therapy
Melanoma is the most deadly form of skin cancer, estimated by the National Cancer Institute to afflict more than 70,000 people in the United States annually and the incidence rate continues to rise. In a study published online ...
Cancer
May 10, 2012 |
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Breaking down cancer's defense for future vaccines
Researchers at the EPFL have identified an important mechanism that could lead to the design of more effective cancer vaccines. Their discovery of a new-found role of the lymphatic system in tumour growth ...
Cancer
Feb 23, 2012 |
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Study shows how immune cells navigate through the skin by sensing graded patterns of immobilized directional cues
A research paper by the group of Michael Sixt, Assistant Professor at the Institute of Science and Technology Austria (IST Austria), published today in Science, provides new insights into how immune cells ...
Medical research
Jan 17, 2013 |
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Preschool within lymphatic vessels
Not only infants crawl. ETH researchers have shown that so-called dendritic cells, important cells of the immune system, use a similar mode of movement more often than previously assumed. The scientists us ...
Medical research
Aug 09, 2012 |
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Genetically modified mice to visualize in vivo inflammation and metastasis
One of the major routes of tumor cell dissemination to form metastasis at distant organs in the body is the lymphatic system. To study this process, still poorly understood, and to gain information on which tumors prefer ...
Cancer
Apr 02, 2012 |
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Evidence strengthens link between NSAIDs and reduced cancer metastasis
A new study reveals key factors that promote the spread of cancer to lymph nodes and provides a mechanism that explains how a common over-the-counter anti-inflammatory medication can reduce the spread of tumor cells through ...
Cancer
Feb 13, 2012 |
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Lymphatic vasculature: A cholesterol removal system
Reverse cholesterol transport is a process in which accumulated cholesterol is removed from tissues, including the artery wall, and transported back to the liver for excretion. Little is known about how cholesterol is removed ...
Medical research
Mar 25, 2013 |
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