Immunology
A Trojan horse? Immune cells ferry deadly fungus from mouse lung into the blood
A report today in PLOS Pathogens shows how inhaled fungal spores exit the lung and trigger a fatal infection in mice.
Jun 27, 2019
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News tagged with macrophages
Oncology & Cancer
Scientists track brain tumor turncoats with advanced imaging
Glioblastomas, the deadliest type of brain tumor in adults, attract "turncoats." These are macrophages, a type of immune cell, which promote tumor progression and mask tumors from the immune system's scrutiny. To better understand ...
Jun 25, 2019
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Inflammatory disorders
Research highlights possible targets to help tackle Crohn's disease
Affecting around 115,000 people in the UK alone, Crohn's Disease is a lifelong condition which sees parts of the digestive system become inflamed. There is no precise cure and causes are believed to vary. But one indicator ...
Jun 17, 2019
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Arthritis & Rheumatism
Preventing cell death as novel therapeutic strategy for rheumatoid arthritis
A collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that death of macrophages, an immune cell type, can trigger the disease. Moreover, they discovered how the ...
May 14, 2019
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Arthritis & Rheumatism
Researchers advance understandings of the cellular mechanisms driving rheumatoid arthritis
Newly identified subsets of cell types present in joint tissue in people with rheumatoid arthritis and how they interact may explain why only some people respond to existing medications, according to two studies by co-senior ...
May 9, 2019
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HIV & AIDS
New angle of attack drives cellular HIV-reservoirs to self-destruction
While current therapies for HIV can successfully manage active infection, the virus can survive in tissue reservoirs, including macrophage cells, and remain a persistent problem. Now, Dr. David Russell, William Kaplan Professor ...
Mar 25, 2019
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Diseases, Conditions, Syndromes
Anti-TB drugs can increase risk of TB re-infection
Current treatments for tuberculosis (TB) are very effective in controlling TB infection caused by Mycobacterium tuberculosis (Mtb). They don't, however, always prevent reinfection. Why this happens is one of the long-standing ...
Mar 22, 2019
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Medical research
Modified immune cells issue alert when detecting cancer in mice
Stanford scientists were able to engineer immune cells known as macrophages to detect and flag cancer in mice. The researchers hope the technique can be used for early cancer diagnostics in humans.
Mar 19, 2019
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Oncology & Cancer
Inside a tumor: Purple bacteria visualize 'big eaters'
Cancer presents an ongoing challenge for physicians, particularly in the diagnosis and treatment of the disease. This is due to tumor heterogeneity, among other things. A team of scientists from the Helmholtz Zentrum Muenchen, ...
Mar 14, 2019
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Immunology
Scientists stumble upon a model to study a lethal complication
More and more hospitalized patients with sepsis are being diagnosed with a deadly complication characterized by high levels of inflammation. A team of Yale researchers has uncovered clues to the cause of this complication—which ...
Feb 11, 2019
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