Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...
Feb 21, 2012
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A mutant gene long thought to accelerate tumor growth in thyroid cancer patients actually inhibits the spread of malignant cells, showing promise for novel cancer therapies, a Mayo Clinic study has found.
Jun 4, 2011
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Researchers with UCLA's Jonsson Comprehensive Cancer Center have discovered a way to amp up the power of killer T-cells, called CD8 cells, making them more functional for longer periods of time and boosting their ability ...
May 10, 2011
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Epithelial ovarian cancer (EOC) is the most lethal disease among gynecologic malignancies. Patients with an advanced disease often relapse due to the development of chemoresistance. Chemotherapy failure is a consequence of ...
Jun 16, 2016
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The body's immune system can recognize and attack cancer cells, but when those are able to overcome this assault, malignant tumors develop in patients. New research led by investigators at Massachusetts General Hospital (MGH) ...
Aug 11, 2021
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Cancers whose cells are riddled with large numbers of DNA mutations often respond favorably to drugs called checkpoint blockers that unleash the immune system against the tumor. But a new study shows that malignant brain ...
Apr 15, 2020
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A new class of immunotherapy shows promising results for fighting the most aggressive form of skin cancer.
Apr 25, 2023
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Aspirin is known to lower risk for some cancers, and a new study led by a UC San Francisco scientist points to a possible explanation, with the discovery that aspirin slows the accumulation of DNA mutations in abnormal cells ...
Jun 18, 2013
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The proliferation of metastases is often the main cause of complications and death from cancer. For the first time, researchers are looking very closely at the development of these metastases themselves, instead of focusing ...
Dec 7, 2011
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(HealthDay) -- Basal cell carcinoma (BCC) on the ear is significantly more likely to be aggressive, and occurs more frequently in men, according to a study published in the May issue of the Journal of the American Academy ...
Apr 18, 2012
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