Immortality gene mutation identifies brain tumors, other cancers
Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research ...
Cancer
Mar 18, 2013 |
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First evidence that obesity gene is risk factor for melanoma
The gene most strongly linked to obesity and overeating may also increase the risk of malignant melanoma – the most deadly skin cancer, reveals research published in Nature Genetics.
Genetics
Mar 04, 2013 |
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Combination of targeted treatment drugs delays resistance in melanoma patients
Combined treatment with two drugs targeting different points in the same growth-factor pathway delayed the development of treatment resistance in patients with BRAF-positive metastatic malignant melanoma. The results of a ...
Cancer
Sep 29, 2012 |
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New mutations driving malignant melanoma discovered
Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't ...
Cancer
Jan 24, 2013 |
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Revolutionary techniques could help harness patients' own immune cells to fight disease
The human body contains immune cells programmed to fight cancer and viral infections, but they often have short lifespans and are not numerous enough to overcome attacks by particularly aggressive malignancies ...
Medical research
Jan 03, 2013 |
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BRAF inhibitor treatment causes melanoma cells to shift how they produce energy
A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...
Cancer
Mar 08, 2013 |
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Researchers discover how melanoma cells circumvent the immune system
Melanoma is so dangerous because it tends to metastasize early on. New treatment approaches utilize, among other things, the ability of the immune defense to search out and destroy malignant cells. Yet this strategy is often ...
Cancer
Oct 10, 2012 |
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New study links tanning beds to non-melanoma skin cancer
Indoor tanning beds can cause non-melanoma skin cancer – and the risk is greater the earlier one starts tanning, according to a new analysis led by UCSF.
Cancer
Oct 02, 2012 |
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Tapeworm DNA contains drug weak spots
For the first time, researchers have mapped the genomes of tapeworms to reveal potential drug targets on which existing drugs could act. The genomes provide a new resource that offers faster ways to develop urgently needed ...
Diseases, Conditions, Syndromes
Mar 13, 2013 |
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Three new gene faults found to increase melanoma risk by 30 percent
An international team of researchers has discovered the first DNA faults linked to melanoma - the deadliest skin cancer - that are not related to hair, skin or eye colour.
Genetics
Oct 09, 2011 |
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Newly identified gene mutation adds to melanoma risk
A major international study has identified a novel gene mutation that appears to increase the risk of both inherited and sporadic cases of malignant melanoma, the most deadly form of skin cancer. The identified mutation occurs ...
Cancer
Nov 13, 2011 |
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Pediatric melanomas are increasing two percent a year
(HealthDay)—The incidence of pediatric melanoma has increased by about 2 percent per year, and this incidence trend is influenced by gender, age, and stage at diagnosis, primary site, and ultraviolet (UV)-B ...
Pediatrics
Apr 16, 2013 |
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Early results show two drugs may be better than one to treat most deadly skin cancer
Adding lung cancer drugs to targeted melanoma treatment could increase survival for certain patients, according to research published in Cancer Discovery today.
Cancer
Feb 12, 2013 |
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Sun starved Brits to risk health this summer
Following some of the coldest and wettest weather on record, around 4.9 million people in the UK (10 per cent) are more likely to risk scorching themselves in strong sun in an attempt to get a tan this summer, ...
Cancer
Apr 29, 2013 |
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Cloned receptor paves way for new breast and prostate cancer treatment
Researchers at Uppsala University have cloned a T-cell receptor that binds to an antigen associated with prostate cancer and breast cancer. T cells that have been genetically equipped with this T-cell receptor have the ability ...
Cancer
Sep 13, 2012 |
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