Oncology & Cancer
'Tiny first responders' use powers for good against skin cancer
Researchers investigating a group of microscopic cells have discovered they can put the brakes on the rapid development of melanoma lesions.
Jun 8, 2021
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News tagged with melanoma cells
Oncology & Cancer
New immunotherapy drug effective for melanoma, other cancers
A new immune checkpoint inhibitor has proven effective in helping save the lives of advanced melanoma patients, a breakthrough that could extend to the treatment of other cancers. Relatlimab is the first immunotherapy treatment ...
Jun 3, 2021
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Oncology & Cancer
Scientists reveal role of genetic switch in pigmentation and melanoma
Despite only accounting for about 1 percent of skin cancers, melanoma causes the majority of skin cancer-related deaths. While treatments for this serious disease do exist, these drugs can vary in effectiveness depending ...
May 18, 2021
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Oncology & Cancer
Investigators identify STING gene methylation allows melanoma to evade the immune system
A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, ...
Apr 8, 2021
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Oncology & Cancer
An amyloid link between Parkinson's disease and melanoma
On the surface, Parkinson's disease—a neurodegenerative disorder—and melanoma—a type of skin cancer—do not appear to have much in common. However, for nearly 50 years, doctors have recognized that Parkinson's disease ...
Apr 7, 2021
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Oncology & Cancer
Novel cancer vaccine targets oncogenes known to evade immunity in melanoma and neuroblastoma models
A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study ...
Apr 2, 2021
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Oncology & Cancer
Scientists identify new biomarkers in patients with malignant melanoma, which could help in its diagnosis and prognosis
A team of researchers has studied the molecular profile of small "messenger" vesicles called exosomes, produced by cancer stem cells (CSCs), which play a key role in the process of carcinogenesis and metastasis in the blood ...
Mar 25, 2021
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Oncology & Cancer
Researchers find cellular evidence behind lasting immune response in some cancer survivors
Some melanoma patients respond very well to immunotherapy, experiencing profound and durable tumor regression. A fraction of these patients will also develop autoimmunity against their normal melanocytes—the cells that ...
Mar 24, 2021
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Oncology & Cancer
Deluge of DNA changes drives progression of fatal melanomas
Melbourne researchers have revealed how melanoma cells are flooded with DNA changes as this skin cancer progresses from early, treatable stages through to fatal end-stage disease.
Mar 22, 2021
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Oncology & Cancer
Sequential treatment with immunotherapy and checkpoint inhibitors prolongs anti-tumor activity
Advanced melanoma is one of the deadliest types of cancer, with a 5-year survival rate of only 27% for patients with distant metastases. Recent advances in targeted therapies and immunotherapies have greatly improved patient ...
Mar 2, 2021
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