Alzheimer's disease & dementia

Modified protein can prevent Alzheimer's disease in mice

The amyloid precursor protein has always been vilified as a major cause of Alzheimer's disease. One of its fragments, the amyloid-beta peptide, can break off and accumulate in the brain, giving rise to the puffy white globs ...

Medical research

Drug to treat malaria could mitigate hereditary hearing loss

The ability to hear depends on proteins to reach the outer membrane of sensory cells in the inner ear. But in certain types of hereditary hearing loss, mutations in the protein prevent it from reaching these membranes. Using ...

Oncology & Cancer

Missing molecule hobbles cell movement

Cells missing a certain protein on their surface can't move normally, UConn researchers report in Science Signaling. The research could give insight into how cells move and repair wounds in normal tissue, as well as how cancer ...

Oncology & Cancer

Pushing closer to a new cancer-fighting strategy

A molecular pathway that's frequently mutated in many different forms of cancer becomes active when cells push parts of their membranes outward into bulging protrusions, Johns Hopkins researchers report in a new study. The ...

Diseases, Conditions, Syndromes

Finally, hope for a syphilis vaccine

Despite efforts to eradicate it, syphilis is on the rise. Until now, most health agencies focused on treating infected people and their sex partners but new discoveries may make a vaccine possible, UConn Health researchers ...

Alzheimer's disease & dementia

Alzheimer's Tau protein forms toxic complexes with cell membranes

The brains of patients with Alzheimer's disease contain characteristic tangles inside neurons. These tangles are formed when a protein called Tau aggregates into twisted fibrils. As a result, the neurons' transport systems ...

Diseases, Conditions, Syndromes

Infection mechanism of Rift Valley fever virus identified

Rift Valley fever virus, transmitted by mosquitoes, is responsible for outbreaks in livestock in Africa and can also be fatal in humans. Scientists from the Institut Pasteur and the CNRS, working with the University of Göttingen, ...

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