News tagged with metabolites
Non-smoking hotel rooms still expose occupants to tobacco smoke
Non-smokers should give hotels that allow smoking in certain rooms a wide berth, say the authors, and instead choose completely smoke free hotels.
Health
May 13, 2013 |
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ECE: Abnormal metabolites found in cured cushing's patients
(HealthDay)—Patients with Cushing's syndrome have abnormal brain metabolites suggestive of neuronal dysfunction even after they appeared to have been cured, according to a study presented at the annual ...
Diseases, Conditions, Syndromes
May 03, 2013 |
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Anti-smoking ads with strong arguments, not flashy editing, trigger part of brain involving behavior change
Researchers from the Perelman School of Medicine at the University of Pennsylvania have shown that an area of the brain that initiates behavioral changes had greater activation in smokers who watched anti-smoking ads with ...
Neuroscience
Apr 23, 2013 |
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Study says more efforts needed to regulate dietary supplements
Dietary supplements accounted for more than half the Class 1 drugs recalled by the U.S. Food and Drug Administration from 2004-12, meaning they contained substances that could cause serious health problems or even death, ...
Health
Apr 18, 2013 |
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Vitamin D not tied to subclinical atherosclerosis in T1DM
(HealthDay)—For individuals with type 1 diabetes, low concentrations of vitamin D metabolites are not associated with an increased risk of subclinical atherosclerosis, according to a study published online ...
Diabetes
Apr 12, 2013 |
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New approach evaluates effect of physical activity on estrogen metabolism in postmenopausal women
Researchers have generated new insights into the ways in which physical activity affects how much estrogen is broken down and secreted in the urine of postmenopausal women. These findings enhance understanding of the potential ...
Cancer
Apr 10, 2013 |
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Researchers discover new link between heart disease and red meat
A compound abundant in red meat and added as a supplement to popular energy drinks has been found to promote atherosclerosis – or the hardening or clogging of the arteries – according to Cleveland Clinic ...
Cardiology
Apr 07, 2013 |
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Vitamin D linked to mitochondrial oxidative function
(HealthDay)—For vitamin D deficient individuals, cholecalciferol therapy is associated with reduced phosphocreatine recovery half-time in skeletal muscle and with improvements in fatigue, according to a ...
Health
Mar 19, 2013 |
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Contaminated diet contributes to phthalate and bisphenol A exposure
While water bottles may tout BPA-free labels and personal care products declare phthalates not among their ingredients, these assurances may not be enough. According to a study published February 27 in the ...
Health
Feb 27, 2013 |
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A natural sense of rhythm: Shifting levels of molecules in the blood provide a snapshot of internal 'body-time'
Anybody who has worked the overnight shift will testify that sometimes the time displayed on the clock is not the same as the one in your head. This disconnect is not merely perception; many physiological ...
Medical research
Jan 18, 2013 |
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Lack of key enzyme in the metabolism of folic acid leads to birth defects
Researchers at The University of Texas at Austin have discovered that the lack of a critical enzyme in the folic acid metabolic pathway leads to neural tube birth defects in developing embryos.
Medical research
Jan 17, 2013 |
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Problems with mineral metabolism linked with kidney disease progression
Abnormalities of mineral metabolism worsen with progressive chronic kidney disease (CKD) and are linked with a higher risk for kidney failure among African Americans, according to a study appearing in an upcoming issue of ...
Diseases, Conditions, Syndromes
Dec 13, 2012 |
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Metabolic biomarkers for preventive molecular medicine
A team of scientists from the Spanish National Cancer Research Centre, led by its director, María Blasco, together with Jose M. Mato, the director of the Center for Cooperative Research in Biosciences, has shown that the ...
Medical research
Dec 04, 2012 |
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Researchers find new target for Alzheimer's drug development
Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.
Alzheimer's disease & dementia
Dec 03, 2012 |
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New risk factor identified for high blood pressure during pregnancy
Preeclampsia is a serious complication of pregnancy and the major cause of death for both mother and child in Europe and the U.S. It affects about one in 20 pregnancies. The main symptoms are high blood pressure and protein ...
Medical research
Nov 26, 2012 |
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Metabolite
Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. A primary metabolite is directly involved in normal growth, development, and reproduction. Alcohol is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.
Examples of primary metabolites produced by industrial microbiology:
The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions.
Metabolites from chemical compounds, whether inherent or pharmaceutical, are formed as part of the natural biochemical process of degrading and eliminating the compounds. The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Profiling metabolites of pharmaceutical compounds, drug metabolism, is an important part of drug discovery, leading to an understanding of any undesirable side effects.
For more information about Metabolite, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
