News tagged with metastatic tumor
Changing cancer's environment to halt its spread
By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces ...
Cancer
May 21, 2013 |
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Amplification of a Stat5 gene produces excess oncogenic protein that drives prostate cancer spread
An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells ...
Cancer
May 07, 2013 |
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A different view of cancer cells: New study measures physical changes in tumor cells as they become metastatic
Most cancer deaths are caused by metastatic tumors, which break free from the original cancer site and spread throughout the body. For that to happen, cancer cells must undergo many genetic and physical changes.
Cancer
Apr 23, 2013 |
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Signature of circulating breast tumor cells that spread to the brain found
Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor ...
Cancer
Apr 10, 2013 |
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Little molecule makes big difference in bladder cancer metastasis
In order to kill, bladder cancer must metastasize, most commonly to the lung – what are the differences between bladder cancers that do and do not make this deadly transition? Research presented by the Director of the University ...
Cancer
Apr 09, 2013 |
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Third-generation device significantly improves capture of circulating tumor cells
A new system for isolating rare circulating tumor cells (CTCs) – living solid tumor cells found at low levels in the bloodstream – shows significant improvement over previously developed devices and does ...
Cancer
Apr 03, 2013 |
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Loss of tumor suppressor SPOP releases cancer potential of SRC-3
Mutations in a protein called SPOP (speckle-type POZ protein) disarm it, allowing another protein called steroid receptor coactivator-3 (SRC-3) to encourage the proliferation and spread of prostate cancer cells, said researchers ...
Cancer
Apr 01, 2013 |
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Researchers help test cancer drug in clinical trial leading to FDA approval
The FDA has approved a thyroid cancer drug successfully tested at Virginia G. Piper Cancer Center Clinical Trials, a partnership of Scottsdale Healthcare and the Translational Genomics Research Institute (TGen).
Cancer
Mar 27, 2013 |
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New cancer 'vaccine' shows future promise in treating and preventing metastatic cancers
Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center. Results from ...
Cancer
Feb 27, 2013 |
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Drug shown to reverse radioiodine resistance in some advanced thyroid cancers
The experimental drug selumetinib may allow some patients with advanced thyroid cancer to overcome resistance to radioiodine (RAI), the most effective therapy for the disease, according to new research from Memorial Sloan-Kettering ...
Cancer
Feb 14, 2013 |
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Researchers use new molecular inhibitors to successfully hit difficult cancer target
Early laboratory tests are the first to successfully use an experimental molecular therapy to block a hard-to-target part of a protein complex linked to several types of invasive cancer.
Cancer
Feb 05, 2013 |
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Personal epigenetic 'signatures' found consistent in prostate cancer patients' metastases
In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient. The discovery of the ...
Cancer
Jan 23, 2013 |
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Controlling spine metastases with tumor 'separation surgery' and high-dose stereotactic radiosurgery
Researchers from Memorial Sloan-Kettering Cancer Center (New York, NY) have found that tumor "separation surgery" followed by high-dose hypofractionated stereotactic radiosurgery (SRS) or high-dose single-fraction SRS is ...
Neuroscience
Jan 22, 2013 |
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Scientists reveal aggressive breast cancer's metastatic path
Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor ...
Cancer
Jan 14, 2013 |
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Fak inhibitor proves effective against brain tumors in preclinical studies, study shows
(Medical Xpress)—Researchers from Roswell Park Cancer Institute (RPCI) have published findings from a preclinical study assessing the effectiveness of a small-molecule inhibitor, CFAK-Y15, in treating some brain cancers. ...
Cancer
Dec 24, 2012 |
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