News tagged with methyl groups

Possible role for Huntington's gene discovered

About 20 years ago, scientists discovered the gene that causes Huntington's disease, a fatal neurodegenerative disorder that affects about 30,000 Americans. The mutant form of the gene has many extra DNA ...

Jan 16, 2013
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New technique could transform epigenetics research

(Medical Xpress) -- Collaboration between scientists at Cambridge University and the Babraham Institute have demonstrated a new technique that will significantly improve scientists' ability to perform epigenetics ...

Apr 26, 2012
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Hopkins team discovers how DNA changes

Using human kidney cells and brain tissue from adult mice, Johns Hopkins scientists have uncovered the sequence of steps that makes normally stable DNA undergo the crucial chemical changes implicated in cancers, psychiatric ...

Apr 14, 2011
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Epigenetic changes may explain chronic kidney disease

The research of physician-scientist Katalin Susztak, MD, PhD, associate professor of Medicine in the Renal Electrolyte and Hypertension Division, at the Perelman School of Medicine, University of Pennsylvania, strives to ...

Nov 22, 2013
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Researchers erase human brain tumor cells in mice

Working with mice, Johns Hopkins researchers have discovered that weeks of treatment with a repurposed FDA-approved drug halted the growth of—and ultimately left no detectable trace of—brain tumor cells taken from adult ...

Sep 23, 2013
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Lifestyle influences metabolism via DNA methylation

An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum München have now identified 28 DNA alterations associated with ...

Sep 20, 2013
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