News tagged with methyl groups

Related topics: genes , gene expression , cancer , dna sequences , dna methylation




Epigenetic reprogramming: Research discovers how epigenetic information could be inherited

New research reveals a potential way for how parents' experiences could be passed to their offspring's genes. The research was published today, 25 January, in the journal Science.

Genetics created Jan 24, 2013 | popularity 4.5 / 5 (4) | comments 4 | with audio podcast

Possible role for Huntington's gene discovered

About 20 years ago, scientists discovered the gene that causes Huntington's disease, a fatal neurodegenerative disorder that affects about 30,000 Americans. The mutant form of the gene has many extra DNA ...

Genetics created Jan 16, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Methylome modifications offer new measure of our 'biological' age

Women live longer than men. Individuals can appear or feel years younger – or older – than their chronological age. Diseases can affect our aging process. When it comes to biology, our clocks clearly tick differently.

Medical research created Nov 21, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Epigenetic analysis of stomach cancer finds new disease subtypes

Researchers at the Duke-NUS Graduate Medical School in Singapore have identified numerous new subtypes of gastric cancer that are triggered by environmental factors.

Cancer created Oct 17, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New technique could transform epigenetics research

(Medical Xpress) -- Collaboration between scientists at Cambridge University and the Babraham Institute have demonstrated a new technique that will significantly improve scientists' ability to perform epigenetics ...

Genetics created Apr 26, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Hopkins team discovers how DNA changes

Using human kidney cells and brain tissue from adult mice, Johns Hopkins scientists have uncovered the sequence of steps that makes normally stable DNA undergo the crucial chemical changes implicated in cancers, psychiatric ...

Medical research created Apr 14, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Mapping the embryonic epigenome

A large, multi-institutional research team involved in the NIH Epigenome Roadmap Project has published a sweeping analysis in the current issue of the journal Cell of how genes are turned on and off to direct early human ...

Genetics created May 09, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Researchers discover link between inherited endocrine tumor syndrome and well-studied cell pathway

(Medical Xpress)—A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1). Individuals with MEN1 are at a substantially increased risk of ...

Cancer created Apr 24, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

New insights into how genes turn on and off

Researchers at UC Davis and the University of British Columbia have shed new light on methylation, a critical process that helps control how genes are expressed. Working with placentas, the team discovered that 37 percent ...

Genetics created Mar 27, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Pioneering study reveals association of chronic pain and broad epigenetic changes

Injuries that result in chronic pain, such as limb injuries, and those unrelated to the brain are associated with epigenetic changes in the brain which persist months after the injury, according to researchers ...

Genetics created Feb 15, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Colon cancer exhibits a corresponding epigenetic pattern in mice and humans

Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between ...

Genetics created Feb 07, 2013 | popularity not rated yet | comments 0 | with audio podcast

Personal epigenetic 'signatures' found consistent in prostate cancer patients' metastases

In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient. The discovery of the ...

Cancer created Jan 23, 2013 | popularity not rated yet | comments 0 | with audio podcast

Epigenomic abnormalities predict patient survival in non-Hodgkins lymphoma

Think of the epigenome like a giant musical mixing board, turning up or down the expression of various genes. A University of Colorado Cancer Center study published today in the journal PLOS Genetics shows that in cancer ...

Genetics created Jan 10, 2013 | popularity not rated yet | comments 0 | with audio podcast

Insight into DNA reprogramming during egg and sperm cell development

Scientists at the Babraham Institute have gained a new understanding of when and how the DNA in developing egg and sperm cells is 'reset', in preparation for making a new embryo. It is well known that small chemical groups ...

Genetics created Dec 06, 2012 | popularity not rated yet | comments 0 | with audio podcast

Blood cells may offer telltale clues in cancer diagnosis

Postdoctoral Research Fellow Devin Koestler is a biostatistician in the Geisel School of Medicine at Dartmouth. He develops and applies statistical methods to large volumes of data, seeking new approaches ...

Cancer created Oct 12, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast