News tagged with microenvironment
Researchers develop sperm-sorting design that may aid couples undergoing in vitro fertilization
(Medical Xpress)—According to the World Health Organization, approximately 70 million couples experience infertility worldwide. Current data suggests that nearly one third of infertility disorders are due ...
Medical research
1 hour ago |
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Changing cancer's environment to halt its spread
By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces ...
Cancer
May 21, 2013 |
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No genetic clock for neuron longevity
(Medical Xpress)—People are living longer than ever before, thanks to medical and technological advances. Unfortunately, aging can be associated with a decrease in brain function. This is because, unlike ...
Neuroscience
Feb 27, 2013 |
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Scientists discover key process that allows colon cancer to metastasize
A team of 17 researchers, led by scientists Eduard Batlle and Elena Sancho in the Colorectal Cancer Laboratory at the Institute for Research in Biomedicine (IRB Barcelona), have determined that the ability ...
Cancer
Nov 12, 2012 |
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Taming physical forces that block cancer treatment
A Massachusetts General Hospital research team has identified factors that contribute to solid stress within tumors, suggesting possible ways to alleviate it, and has developed a simple way to measure such pressures.
Cancer
Sep 20, 2012 |
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Study identifies blood-forming stem cells' growth
Scientists with the new Children's Research Institute at UT Southwestern Medical Center have identified the environment in which blood-forming stem cells survive and thrive within the body, an important step toward increasing ...
Medical research
Jan 25, 2012 |
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How some cancers 'poison the soil' to block metastasis
Cancer spread or metastasis can strike unprecedented fear in the minds of cancer patients. The "seed and the soil" hypothesis proposed by Stephen Paget in 1889 is now widely accepted to explain how cancer cells (seeds) are ...
Cancer
Apr 30, 2013 |
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Scientists define a new mechanism leading to tumor hypoxia
An article published recently in Tumor Microenvironment and Therapy - an open access journal by Versita, defines a novel mechanism of tumor hypoxia induced by the longitudinal gradient of residual oxygen along tumor vessel ...
Cancer
May 09, 2013 |
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Molecular probes identify changes in fibronectin that may lead to disease
Fibronectin plays a major role in wound healing and embryonic development. The protein, which is located in the extracellular matrix of cells, has also been linked to pathological conditions including cancer ...
Medical research
Apr 24, 2012 |
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Scientists identify crucial cell and signaling pathway in placental blood stem cell niche
(Medical Xpress) -- UCLA stem-cell researchers have identified a certain type of cell and a signaling pathway in the placental niche that play a key role in stopping blood stem cells from differentiating into mature blood ...
Medical research
Mar 01, 2012 |
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Tumor microenvironment helps skin cancer cells resist drug treatment
One of cancer's most frightening characteristics is its ability to return after treatment. In the case of many forms of cancer, including the skin cancer known as melanoma, tailored drugs can eradicate cancer cells in the ...
Cancer
Jul 04, 2012 |
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Embryonic blood vessels that make blood stem cells can also make beating heart muscles
UCLA stem cell researchers have found for the first time a surprising and unexpected plasticity in the embryonic endothelium, the place where blood stem cells are made in early development.
Medical research
Aug 02, 2012 |
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Tumor cells engineer acidity to drive cell invasion
Researchers at Moffitt Cancer Center and colleagues at Wayne State University School of Medicine investigated the acidity in solid tumors to determine if pH levels play a role in cancer cell invasion in surrounding tissues. ...
Cancer
Jan 25, 2013 |
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Diabetes distresses bone marrow stem cells by damaging their microenvironment
New research has shown the presence of a disease affecting small blood vessels, known as microangiopathy, in the bone marrow of diabetic patients. While it is well known that microangiopathy is the cause of renal damage, ...
Diabetes
Jan 31, 2013 |
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Researchers reveal how cancer cells change once they spread to distant organs
Oncologists have known that in order for cancer cells to spread, they must transform themselves so they can detach from a tumor and spread to a distant organ. Now, scientists at Weill Cornell Medical College have revealed ...
Cancer
Feb 22, 2012 |
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