Chromosomes are capped by long, repetitive DNA sequences called telomeres. These caps prevent genomic damage by insulating against the steady shortening of DNA ends that naturally accompanies replication. Once mature, cells ...
Feb 27, 2013
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(Medical Xpress)—One of the hallmarks of cancer is unchecked cellular growth. Fortunately, our cells contain a number of tumor suppressor proteins, including the cell cycle regulator p21, to keep cell growth in check. The ...
Feb 13, 2013
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Hydrogen sulfide (H2S) may play a wide-ranging role in staving off aging, according to a paper published online ahead of print in the journal Molecular and Cellular Biology. In this review article, a team from China explores ...
Jan 29, 2013
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Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work ...
Jan 29, 2013
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(Medical Xpress)—According to the Centers for Disease Control, nearly 3 of every 100 babies in the U.S. are born with a birth defect. Among boys, one of the most common defects is the displacement of the urethral opening ...
Jan 16, 2013
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The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of tumorigenesis. ...
Jan 16, 2013
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(Medical Xpress)—As anyone familiar with the X-Men knows, mutants can be either very good or very bad—or somewhere in between. The same appears true within cancer cells, which may harbor hundreds of mutations that set ...
Dec 27, 2012
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An international project lead by the Molecular and Cell Biology Institute of Porto University with the participation of researchers from IMIM (Hospital del Mar Medical Research Institute) has, for the first time ever, deciphered ...
Dec 11, 2012
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Cancer biologists have known for decades that even the most potent cancer-causing genes do not act alone. Yet, identifying which combinations of genetic changes can cause a tumor to form and disease to progress remains a ...
Dec 5, 2012
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Researchers from Inserm and CNRS from the Institute for genetics and molecular and cellular biology (IGBMC) and from the Research Institute at the Strasbourg school of biotechnology (Irebs) have focussed their efforts on ...
Oct 30, 2012
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