News tagged with molecular mechanism
Related topics: neurons , brain , nerve cells , protein , proceedings of the national academy of sciences
Researchers identify new strategy for interfering with potent cancer-causing gene
Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible ...
Cancer
Feb 11, 2013 |
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Colon cancer exhibits a corresponding epigenetic pattern in mice and humans
Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between ...
Genetics
Feb 07, 2013 |
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New computational pipeline analyzes tumor images, may help predict response to cancer therapy
(Medical Xpress)—How's this for big data: A whole-slide image of a tumor section can be ten billion pixels. There can be thousands of such images in the tumor cohorts maintained by The Cancer Genome Atlas ...
Cancer
Feb 01, 2013 |
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Sirtuin protein discovery opens door to potential 'molecular fountain of youth'
A new study led by researchers at the University of California, Berkeley, represents a major advance in the understanding of the molecular mechanisms behind aging while providing new hope for the development of targeted treatments ...
Medical research
Jan 31, 2013 |
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New target for treating wide spectrum of cancers
(Medical Xpress)—UC Irvine biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. The finding heralds a new treatment ...
Cancer
Jan 31, 2013 |
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Researchers identify possible drug target in breast cancer metastasis
The spread of breast cancer to distant organs within the body, an event that often leads to death, appears in many cases to involve the loss of a key protein, according to UC San Francisco researchers, whose new discoveries ...
Cancer
Jan 27, 2013 |
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Genes provide clues to gender disparity in human hearts
Healthy men and women show little difference in their hearts, except for small electrocardiographic disparities. But new genetic differences found by Washington University in St. Louis researchers in hearts with disease could ...
Cardiology
Jan 24, 2013 |
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Beta-catenin molecule is required for tooth root formation
Today, the International and American Associations for Dental Research (IADR/AADR) published a paper titled "ß-catenin is Required in Odontoblasts for Tooth Root Formation." The paper, written by lead authors Tak-Heun Kim ...
Dentistry
Jan 23, 2013 |
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The skin aging regulator
Despite progress in regenerative medicine, with age, the skin loses its properties in an irreversible manner. The ATIP-Avenir team "Epidermal homeostasis and tumorigenesis" directed by Chloé Féral, an Inserm ...
Medical research
Jan 22, 2013 |
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Diabetic fruit flies support buzz about dietary sugar dangers
Regularly consuming sucrose—the type of sugar found in many sweetened beverages—increases a person's risk of heart disease. In a study published January 10 in the journal PLOS Genetics, researchers at San ...
Genetics
Jan 17, 2013 |
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Cancer biology: Keeping bad company
The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of ...
Cancer
Jan 16, 2013 |
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Scientists reveal aggressive breast cancer's metastatic path
Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor ...
Cancer
Jan 14, 2013 |
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Foot soldiers of the immune system: IFIT antiviral protein recognizes foreign RNA and blocks viral infections
Researchers at McGill University and the Research Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences have discovered the molecular blueprint behind the IFIT protein. This key protein enables the human ...
Immunology
Jan 13, 2013 |
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Inherited retinal disease research may lead to treatment
Inherited retinal disease is a major cause of vision impairment in early life - and a researcher at The University of Western Australia hopes a study in which he was involved will contribute towards the development ...
Medical research
Jan 08, 2013 |
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GW professor discovers new information in the understanding of autism and genetics
(Medical Xpress)—Research out of the George Washington University (GW), published in the journal Proceedings of the National Academy of Sciences (PNAS), reveals another piece of the puzzle in a genetic developmental disorder that ...
Autism spectrum disorders
Jan 03, 2013 |
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