News tagged with molecular pathology


New animal model gives insights into mechanisms of Parkinson's disease pathogenesis

In Parkinson's disease, the protein "alpha-synuclein" aggregates and accumulates within neurons. Specific areas of the brain become progressively affected as the disease develops and advances. The mechanism underlying this ...

Parkinson's & Movement disorders created 1 hour ago | popularity not rated yet | comments 0

Patenting the human genome

Can human genes be patented? That was the question posed by Alan J. Snyder, vice president and associate provost for research and graduate studies at Lehigh, and Lee Kaplan, scientific director of cellular and molecular genetics ...

Genetics created 5 hours ago | popularity 4 / 5 (1) | comments 0

Are human genes patentable?

(Medical Xpress)—On April 15, the Supreme Court will hear oral argument in Association for Molecular Pathology v. Myriad Genetics, a case that could answer the question, "Under what conditions, if any, ...

Genetics created Apr 11, 2013 | popularity 4.3 / 5 (6) | comments 16 | with audio podcast

Rejected Alzheimer's drug shows new potential

An international team of scientists led by researchers at Mount Sinai School Medicine have discovered that a drug that had previously yielded conflicting results in clinical trials for Alzheimer's disease effectively stopped ...

Psychology & Psychiatry created Jul 31, 2012 | popularity 4 / 5 (1) | comments 1 | with audio podcast

A key gene for brain development

(Medical Xpress)—Neurobiologists at the Research institute of Molecular Pathology (IMP) in Vienna have discovered one of the key genes required to make a brain. Mutations in this gene, called TUBB5, cause ...

Genetics created Dec 14, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Research reveals Huntington's hope

(Medical Xpress)—Researchers in Scotland and Germany have discovered a molecular mechanism that shows promise for developing a cure for Huntington's Disease (HD).

Neuroscience created Feb 27, 2013 | popularity 3 / 5 (1) | comments 0 | with audio podcast

Researchers discover surprising new roles for a key regulatory enzyme of blood pressure

At the 1st ECRC "Franz-Volhard" Symposium on September 7, 2012 at the Max Delbrück Center for Molecular Medicine (MDC) in Berlin-Buch, Professor Ken Bernstein reported that in mice an excess of ACE led to a much stronger ...

Medical research created Sep 08, 2012 | popularity not rated yet | comments 0

Study shows how high-fat diets increase colon cancer risk

Epidemiologists have long warned that, in addition to causing obesity, eating too much fat and sugar puts a person at greater risk for colon cancer. Now, researchers at Temple University have established a link that may explain ...

Cancer created Mar 07, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers define how a gene mutated in Parkinson's disease may normally function to ensure neuronal health

(Medical Xpress)—Cell biologists studying Parkinson's disease are training their sights on mitochondria, the energy source of the cell, whose activity in neurons appears to go awry in this devastating neurodegenerative ...

Medical research created Mar 22, 2013 | popularity 4 / 5 (1) | comments 0

Protein central to cancer stem cell formation provides new potential target

Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.

Cancer created Feb 13, 2013 | popularity 5 / 5 (1) | comments 0

Novel test streamlines testing for Huntington Disease

A new test may help to streamline genetic testing for Huntington Disease (HD) by generating accurate results, avoiding unnecessary additional testing, and improving turnaround time. The test, which uses chimeric or triplet ...

Genetics created Feb 13, 2013 | popularity not rated yet | comments 0 | with audio podcast

How the brain forms categories

Neurobiologists at the Research Institute of Molecular Pathology (IMP) in Vienna investigated how the brain is able to group external stimuli into stable categories. They found the answer in the discrete ...

Neuroscience created Oct 20, 2012 | popularity 3.8 / 5 (5) | comments 1

Insulin therapy may help repair atherosclerotic lesions in diabetic patients

New research reveals that insulin applied in therapeutic doses selectively stimulates the formation of new elastic fibers in cultures of human aortic smooth muscle cells. These results advance the understanding of the molecular ...

Diseases, Conditions, Syndromes created Jan 09, 2012 | popularity 5 / 5 (1) | comments 0

Enzyme replacement therapy shows promising results in X-linked myotubular myopathy

A collaborative research team including a Medical College of Wisconsin (MCW) pediatric neuropathologist successfully mitigated some of the effects of a muscular disease by using a new targeted enzyme replacement therapy strategy ...

Genetics created Jan 22, 2013 | popularity 5 / 5 (1) | comments 0

Aurora-A hinders tumor-suppressor to allow chemotherapy resistance

A protein abundantly found in treatment-resistant cancers holds an important tumor-suppressor out of the cell nucleus, where it would normally detect DNA damage and force defective cells to kill themselves, a team of scientists ...

Cancer created Feb 27, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast