Hope in stopping melanoma from spreading: Study shows that inhibiting key protein prevents metastasis to lungs in mice
(Medical Xpress)—Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation ...
Cancer
Mar 05, 2013 |
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A coordinated response to cardiac stress
Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain ...
Cardiology
Mar 01, 2013 |
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Parkinson's disease: Parkin protects from neuronal cell death
Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death.
Parkinson's & Movement disorders
Mar 01, 2013 |
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Study identifies growth factor essential to the most common malignant pediatric brain tumor
A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...
Cancer
Feb 28, 2013 |
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Study reveals molecular networks of mental health disorders
(Medical Xpress)—Early diagnosis and intervention for ADHD, autism and schizophrenia could be made possible after Australian scientists discovered the molecular networks in the brain showing psychiatric and developmental ...
Psychology & Psychiatry
Feb 27, 2013 |
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Novel combination therapy shuts down escape route, killing glioblastoma tumor cells
Glioblastoma, the most common and lethal form of brain tumor in adults, is challenging to treat because the tumors rapidly become resistant to therapy. As cancer researchers are learning more about the causes of tumor cell ...
Cancer
Feb 26, 2013 |
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Genome-wide imaging study identifies new gene associated with Alzheimer's plaques
A study combining genetic data with brain imaging, designed to identify genes associated with the amyloid plaque deposits found in Alzheimer's disease patients, has not only identified the APOE gene—long ...
Alzheimer's disease & dementia
Feb 20, 2013 |
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Researchers create new air sacs in mouse model of emphysema using novel growth factor
In a study of mice, researchers at Johns Hopkins have identified a new molecular pathway involved in the growth of tiny air sacs called alveoli that are crucial for breathing. The scientists say their experiments may lead ...
Medical research
Feb 14, 2013 |
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Protein central to cancer stem cell formation provides new potential target
Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.
Cancer
Feb 13, 2013 |
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Molecular master switch for pancreatic cancer identified, potential predictor of treatment outcome
A recently described master regulator protein may explain the development of aberrant cell growth in the pancreas spurred by inflammation
Cancer
Feb 12, 2013 |
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Experimental drug combination selectively destroys lymphoma cells
Laboratory experiments conducted by scientists at Virginia Commonwealth University Massey Cancer Center suggest that a novel combination of the drugs ibrutinib and bortezomib could potentially be an effective ...
Cancer
Feb 06, 2013 |
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MicroRNA molecule may serve as biomarker, target for brain metastases in breast cancer patients
Researchers have identified two molecules that could potentially serve as biomarkers in predicting brain metastases in patients with breast cancer, according to data published in Cancer Research, a publication of the Americ ...
Cancer
Feb 05, 2013 |
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Blood vessel cells coax colorectal cancer cells into more dangerous state
Blood vessels that supply oxygen and nutrients to tumors can also deliver something else - a signal that strengthens nearby cancer cells, making them more resistant to chemotherapy, more likely to spread to other organs and ...
Cancer
Feb 01, 2013 |
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Researchers identify possible drug target in breast cancer metastasis
The spread of breast cancer to distant organs within the body, an event that often leads to death, appears in many cases to involve the loss of a key protein, according to UC San Francisco researchers, whose new discoveries ...
Cancer
Jan 27, 2013 |
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Right target, but missing the bulls-eye for Alzheimer's
(Medical Xpress)—Alzheimer's disease is the most common cause of late-life dementia. The disorder is thought to be caused by a protein known as amyloid-beta, or Abeta, which clumps together in the brain, forming plaques ...
Alzheimer's disease & dementia
Jan 24, 2013 |
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