Scientists find protein that reins in runaway network
Marked for death with molecular tags that act like a homing signal for a cell's protein-destroying machinery, a pivotal enzyme is rescued by another molecule that sweeps the telltale targets off in the nick of time.
Medical research
Jan 22, 2013 |
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Evidence mounts for role of mutated genes in development of schizophrenia
Johns Hopkins researchers have identified a rare gene mutation in a single family with a high rate of schizophrenia, adding to evidence that abnormal genes play a role in the development of the disease.
Genetics
Jan 22, 2013 |
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New discovery in autism-related disorder reveals key mechanism in brain development and disease
A new finding in neuroscience for the first time points to a developmental mechanism linking the disease-causing mutation in an autism-related disorder, Timothy syndrome, and observed defects in brain wiring, according to ...
Neuroscience
Jan 14, 2013 |
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The pain puzzle: Uncovering how morphine increases pain in some people
For individuals with agonizing pain, it is a cruel blow when the gold-standard medication actually causes more pain. Adults and children whose pain gets worse when treated with morphine may be closer to a solution, based ...
Neuroscience
Jan 06, 2013 |
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Scientists find new molecule to target in pancreatic cancer treatment
Researchers at Mayo Clinic in Florida have identified a new target to improve treatment of pancreatic ductal adenocarcinoma cancer, which accounts for more than 95 percent of pancreatic cancer cases. This fast-growing, often ...
Cancer
Jan 03, 2013 |
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Scientists home in on cause of osteoarthritis pain
Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could ...
Arthritis & Rheumatism
Dec 27, 2012 |
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Scientists find mechanism that triggers immune responses to DNA
(Medical Xpress)—Free-floating pieces of DNA in a cell's watery interior can mean bad things: invading viruses, bacteria, or parasites, ruptured cellular membranes, or disease. Genetic material is meant to be contained ...
Medical research
Dec 21, 2012 |
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Mount Sinai grad student, 25, named to Forbes '30 Under 30' in Science and Healthcare
Jillian Shapiro, a third-year graduate student at the Icahn School of Medicine at Mount Sinai, has been named to the second annual Forbes "30 Under 30" list in "Science and Health." The honorees "reflect the way that the he ...
Medical research
Dec 20, 2012 |
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Ability to chart the molecular progress of diabetes brings personalized medicine closer to realization
Researchers in Singapore have succeeded in tracking, for the first time, the molecular changes caused by type 2 diabetes that affect how the body handles glucose production in the liver. In a series of experiments ...
Diabetes
Dec 19, 2012 |
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Scientists identify liposarcoma tumors that respond to chemotherapy
Liposarcoma, the most common type of sarcoma, is an often lethal form of cancer that develops in fat cells. It is particularly deadly, in part, because the tumors are not consistently visible with positron emission tomography ...
Cancer
Dec 10, 2012 |
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Combining two genome analysis approaches supports immune system contribution to autism
Researchers using novel approaches and methodologies of identifying genes that contribute to the development of autism have found evidence that disturbances in several immune-system-related pathways contribute to development ...
Autism spectrum disorders
Dec 06, 2012 |
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Scientists find regulator linking exercise to bigger, stronger muscles
Scientists at Dana-Farber Cancer Institute have isolated a previously unknown protein in muscles that spurs their growth and increased power following resistance exercise. They suggest that artificially raising the protein's ...
Medical research
Dec 06, 2012 |
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Discovery of pathway leading to depression reveals new drug targets
Scientists have identified the key molecular pathway leading to depression, revealing potential new targets for drug discovery, according to research led by King's College London's Institute of Psychiatry. The study, published ...
Neuroscience
Dec 06, 2012 |
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International study points to inflammation as a cause of plaque buildup in heart vessels
Fifteen new genetic regions associated with coronary artery disease have been identified by a large, international consortium of scientists—including researchers at the Stanford University School of Medicine—taking a ...
Genetics
Dec 02, 2012 |
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Research may explain why some people with schizophrenia do not respond to treatment
(Medical Xpress)—New research suggests that the molecular mechanism leading to schizophrenia may be different in patients who fail to respond to anti-psychotic medication compared to patients who do respond.
Psychology & Psychiatry
Nov 29, 2012 |
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