News tagged with molecular switch

Related topics: cells , protein , molecules

Two sides of a safety switch

Swiss researchers have discovered a new, surprising link between chloracne and a molecule that protects cells against stress: if Nrf2 gets out of control, disfiguring cysts form on the skin.

Feb 06, 2014
popularity 5 / 5 (1) | comments 0

New knowledge on molecular mechanisms behind breast cancer

Researchers at University of Copenhagen have gained more insight into the molecular mechanisms of importance for, for example, cancer cell growth and metastasis. The research objective is improved and more targeted drugs. ...

Sep 25, 2013
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New inhibitor blocks the oncogenic protein KRAS

One of the major goals in the development of anti-cancer treatments is to find an inhibitor effective against the oncogenic protein known as KRAS. Despite decades of active agent research, efforts to intercede ...

Aug 09, 2013
popularity 5 / 5 (3) | comments 0 | with audio podcast

Heading for regeneration

The rabbit can't do it, neither can a frog, but zebrafish and axolotls can and flatworms are true masters of the craft: Regeneration. Why some animals can re-grow lost body parts or organs while others cannot ...

Jul 24, 2013
popularity 4.6 / 5 (10) | comments 0 | with audio podcast

Source of tumor growth in aggressive prostate cancer found

Researchers have discovered a molecular switch that explains, at least in part, how some fast-growing prostate cancers become resistant to hormone treatment, a new study conducted in human cell cultures and mice finds. The ...

Jun 17, 2013
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Molecular switch

A molecular switch is a molecule that can be reversibly shifted between two or more stable states. The molecules may be shifted between the states in response to changes in e.g. pH, light, temperature, an electrical current, microenvironment, or the presence of a ligand. In some cases, a combination of stimuli are utilized. The oldest forms of synthetic molecular switches are pH indicators, which display distinct colors as a function of pH. Currently synthetic molecular switches are of interest in the field of nanotechnology for application in molecular computers. Molecular switches are also important to in biology because many biological functions are based on it, for instance allosteric regulation and vision. They are also one of the simplest examples of molecular machines.

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