News tagged with molecular switch
Structure of vital protein complex, G protein-coupled receptors, described in unprecedented detail
Three international teams of scientists, led by researchers at the University of California San Diego, University of Michigan and Stanford University, have published a trio of papers describing in unprecedented ...
Medical research
Sep 28, 2011 |
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Team identifies molecular switch enabling immune cells to better fight disease
A research team led by the La Jolla Institute for Allergy & Immunology has discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against ...
Immunology
Jan 20, 2013 |
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New genetic link found between normal fetal growth and cancer
Two researchers at the National Institutes of Health discovered a new genetic link between the rapid growth of healthy fetuses and the uncontrolled cell division in cancer. The findings shed light on normal development and ...
Genetics
Apr 09, 2013 |
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New study says molecular 'switch' may play role in tumor suppression
Newly published research by Indiana University structural biologist Joel Ybe and colleagues identifies a "topology switch" in the protein clathrin, the function of which may shed light on molecular processes involved in tumor ...
Cancer
Jan 13, 2013 |
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Preclinical study identifies 'master' proto-oncogene that regulates ovarian cancer metastasis
Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins – known as Src – leads to ovarian cancer progression when exposed ...
Cancer
Jan 29, 2013 |
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Molecular 'on-off' switch for Parkinson's disease discovered
(Medical Xpress) -- Scientists at the Medical Research Council (MRC) Protein Phosphorylation Unit at the University of Dundee have discovered a new molecular switch that acts to protect the brain from developing Parkinson's ...
Parkinson's & Movement disorders
May 23, 2012 |
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Discovery of insulin switches in pancreas could lead to new diabetes drugs
Researchers at the Salk Institute have discovered how a hormone turns on a series of molecular switches inside the pancreas that increases production of insulin.
Medical research
Sep 26, 2011 |
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Scientists find molecular link to obesity and insulin resistance in mice
Flipping a newly discovered molecular switch in white fat cells enabled mice to eat a high-calorie diet without becoming obese or developing the inflammation that causes insulin resistance, report scientists ...
Medical research
Sep 27, 2012 |
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Molecular switch identified that controls key cellular process
The body has a built-in system known as autophagy, or 'self-eating,' that controls how cells live or die. Deregulation of autophagy is linked to the development of human diseases, including neural degeneration and cancer.
Medical research
Aug 01, 2012 |
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Scientists establish a new class of anti-diabetic compound
In a joint study, scientists from The Scripps Research Institute and Harvard University's Dana-Farber Cancer Institute have established a new class of anti-diabetic compound that targets a unique molecular switch.
Medical research
Sep 04, 2011 |
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Researchers discover faulty molecular switch that cause infertility, miscarriage
Scientists have discovered an enzyme that acts as a 'fertility switch', in a study published in Nature Medicine today. High levels of the protein are associated with infertility, while low levels make a woman more likely ...
Medical research
Oct 16, 2011 |
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Researchers find new culprit in castration-resistant prostate cancer
Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They ...
Cancer
Dec 13, 2012 |
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Scientists reveal aggressive breast cancer's metastatic path
Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor ...
Cancer
Jan 14, 2013 |
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Flip of a single molecular switch makes an old brain young
The flip of a single molecular switch helps create the mature neuronal connections that allow the brain to bridge the gap between adolescent impressionability and adult stability. Now Yale School of Medicine ...
Neuroscience
Mar 06, 2013 |
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Scientists discover how an out-of-tune protein leads to muscle demise in heart failure
A new Johns Hopkins study has unraveled the changes in a key cardiac protein that can lead to heart muscle malfunction and precipitate heart failure.
Cardiology
Sep 12, 2012 |
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Molecular switch
A molecular switch is a molecule that can be reversibly shifted between two or more stable states. The molecules may be shifted between the states in response to changes in e.g. pH, light, temperature, an electrical current, microenvironment, or the presence of a ligand. In some cases, a combination of stimuli are utilized. The oldest forms of synthetic molecular switches are pH indicators, which display distinct colors as a function of pH. Currently synthetic molecular switches are of interest in the field of nanotechnology for application in molecular computers. Molecular switches are also important to in biology because many biological functions are based on it, for instance allosteric regulation and vision. They are also one of the simplest examples of molecular machines.
For more information about Molecular switch, read the full article at
Wikipedia.
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