News tagged with mouse model
Related topics: stem cells , cancer cells , cells , immune cells , animal model
Autism model in mice linked with genetics
For the first time, researchers have linked autism in a mouse model of the disease with abnormalities in specific regions of the animals' chromosomes. The regions contain genes associated with aberrant brain development and ...
Autism spectrum disorders
Apr 15, 2013 |
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Research sheds new light on traumatic brain injuries
Even a mild injury to the brain can have long lasting consequences, including increased risk of cognitive impairment later in life. While it is not yet known how brain injury increases risk for dementia, there are indications ...
Neuroscience
Apr 15, 2013 |
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Promising new antibiotic targets potentially deadly gut infections
(Medical Xpress)—Researchers at the University of Virginia School of Medicine have developed a promising new antibiotic to treat potentially deadly gastrointestinal infections without harming the beneficial probiotic bacteria ...
Diseases, Conditions, Syndromes
Apr 12, 2013 |
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New genetic screen paves the way for long-sought treatments for liver disease
Chronic liver failure is a major health problem that causes about one million deaths around the world each year. A study published April 11th by Cell Press in the journal Cell reveals a new type of screen for identifying genes ...
Medical research
Apr 11, 2013 |
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Fractalkine: New protein target for controlling diabetes
Researchers at the University of California, San Diego School of Medicine have identified a previously unknown biological mechanism involved in the regulation of pancreatic islet beta cells, whose role is to produce and release ...
Diabetes
Apr 11, 2013 |
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New findings on the brain's immune cells during Alzheimer's disease progression
The plaque deposits in the brain of Alzheimer's patients are surrounded by the brain's own immune cells, the microglia. This was already recognized by Alois Alzheimer more than one hundred years ago. But ...
Alzheimer's disease & dementia
Apr 11, 2013 |
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Study unravels central mystery of Alzheimer's disease
Scientists at The Scripps Research Institute (TSRI) have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how ...
Neuroscience
Apr 10, 2013 |
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Producing new neurones under all circumstances: A challenge that is just a mouse away
Improving neurone production in elderly persons presenting with a decline in cognition is a major challenge facing an ageing society and the emergence of neuro-degenerative conditions such as Alzheimer's disease. INSERM and ...
Medical research
Apr 09, 2013 |
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Six2 homeoprotein allows breast cancer cells to detach and metastasize
In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrate ...
Cancer
Apr 09, 2013 |
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K9 osteosarcoma samples identify drivers of metastasis in pediatric bone cancer
Human osteosarcoma samples are hard to come by, making the disease difficult to study. However, K9 bone cancer is genetically indistinguishable from the human form of the disease, and over 10,000 canine patients develop the ...
Cancer
Apr 09, 2013 |
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New target plus new drug equals death of melanoma cells
Collaborative research presented by the University of Colorado Cancer Center, the University of North Carolina at Chapel Hill, Harvard Medical School and the University of Pittsburgh, at the American Association for Cancer ...
Cancer
Apr 09, 2013 |
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Intermittent treatment with vemurafenib may prevent lethal drug resistance in melanoma
Vemurafenib-resistant tumors in patients with melanoma showed reduced growth after cessation of treatment, and in animal models, drug resistance was prevented by intermittent treatment, according to data presented at the ...
Cancer
Apr 08, 2013 |
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Preclinical study indicates potential for novel inhibitor to overcome drug resistance induced by RAF, MEK inhibitors
A new class of investigational medicines may help to treat patients with cancers driven by mutations in genes such as BRAF or KRAS/NRAS, including those patients who have become resistant to therapies that target BRAF directly, ...
Cancer
Apr 08, 2013 |
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Forget about plaque when diagnosing Alzheimer's Disease
(Medical Xpress)—An Australian study has shown that plaque, long considered to be the hallmark of Alzheimer's disease, is one of the last events to occur in the Alzheimer's brain. This finding will impact the current debate ...
Alzheimer's disease & dementia
Apr 03, 2013 |
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Feeling hungry may protect the brain against Alzheimer's disease, study finds
The feeling of hunger itself may protect against Alzheimer's disease, according to study published today in the journal PLOS ONE. Interestingly, the results of this study in mice suggest that mild hunger ...
Alzheimer's disease & dementia
Apr 03, 2013 |
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