mRNA drugs offer a promising new approach to deliver therapeutic replacement proteins, and novel strategies designed to engineer more stable and active proteins are further enhancing the potential of mRNA therapies. Specific ...
Mar 30, 2018
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A team of Japanese researchers will reveal study results Monday at the Experimental Biology 2012 meeting that show how acupuncture therapy mitigates skeletal muscle loss and holds promise for those seeking improved mobility ...
Apr 23, 2012
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Medicines that are based on mRNAs and proteins—particularly vaccines and antibodies—are time-intensive and costly to make. The challenge is in producing the necessary mRNAs and proteins in large enough amounts at low ...
Feb 22, 2023
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Researchers in Japan have shown that several different classes of antidepressants increase early growth responses in astrocytes, star-shaped glial cells, which could help develop new treatments.
Sep 15, 2015
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Cancer is a disease of dysregulated gene expression. Now, researchers from Jefferson (Philadelphia University + Thomas Jefferson University) find that a new, large category of molecules called transfer RNA (tRNA)-derived ...
Apr 17, 2019
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Rats are commonly used in nonclinical pharmaceutical studies to investigate the safety, efficacy and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via ...
Feb 21, 2019
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In order to kill, bladder cancer must metastasize, most commonly to the lung – what are the differences between bladder cancers that do and do not make this deadly transition? Research presented by the Director of the University ...
Apr 9, 2013
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Over the last decade, neurobiology has been focused on the functioning of neural networks rather than single nerve cells. It is at this level that the key functions of the brain are performed, including processing, storage ...
Jun 14, 2018
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In a study published in iScience, Professor Akiyoshi Fukamizu of the University of Tsukuba has reported the discovery of the important role of PRMT1 in dilated cardiomyopathy (DCM).
Oct 16, 2018
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A recent study published in Oncotarget found molecular subtypes based on copy number, DNA methylation, and mRNA expression had variable proliferation levels, the highest correlating with decreased survival.
Dec 11, 2019
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