A new study led by UC Davis MIND Institute researchers confirms that brain development in people with autism differs from those with typical neurodevelopment. According to the study published in PNAS, these differences are ...
Mar 3, 2023
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Alternative polyadenylation (APA) is an RNA processing mechanism that regulates gene expression by generating different ends on RNA transcripts of the same gene. Though it affects more than half of human genes, the significance ...
Jul 20, 2021
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One of the big challenges in neurobiology is cell classification, a problem compounded by the fact that the same cell type can look different depending on the method of analysis used to classify it—whether by cell shape, ...
Jan 28, 2019
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By studying both the physical and genomic features of cancer cells, MIT researchers have come up with a new way to investigate why some cancer cells survive drug treatment while others succumb.
Nov 30, 2018
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(Medical Xpress)—EPFL scientists have developed a "guide" that can be used to precisely predict the number of proteins a given gene will produce under varying conditions. This work will help biologists to engineer cells.
Aug 19, 2013
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Researchers at the University of California, San Diego School of Medicine have uncovered new details of an unusual biological mechanism in the brains of diverse species that not only helps regulate how their brains develop, ...
May 19, 2011
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Medicines that are based on mRNAs and proteins—particularly vaccines and antibodies—are time-intensive and costly to make. The challenge is in producing the necessary mRNAs and proteins in large enough amounts at low ...
Feb 22, 2023
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Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs, are degraded. By reducing errors in gene expression, it serves as an RNA quality ...
Feb 3, 2022
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Cancer is a disease of dysregulated gene expression. Now, researchers from Jefferson (Philadelphia University + Thomas Jefferson University) find that a new, large category of molecules called transfer RNA (tRNA)-derived ...
Apr 17, 2019
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Rats are commonly used in nonclinical pharmaceutical studies to investigate the safety, efficacy and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via ...
Feb 21, 2019
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