News tagged with mutant mice

Related topics: stem cells




Genetic mutation linked with typical form of migraine

A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.

Genetics created May 01, 2013 | popularity 4.5 / 5 (2) | comments 1 | with audio podcast

Team finds mechanism that regulates production of energy-burning brown fat

Joslin scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings, which appear in the upcoming issue ...

Medical research created Mar 13, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Novel storage mechanism allows command, control of memory

(Medical Xpress)—Introductions at a party seemingly go in one ear and out the other. However, if you meet someone two or three times during the party, you are more likely to remember his or her name. Your ...

Neuroscience created Mar 05, 2013 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Epigenetic culprit in Alzheimer's memory decline

In a mouse model of Alzheimer's disease, memory problems stem from an overactive enzyme that shuts off genes related to neuron communication, a new study says.

Medical research created Feb 29, 2012 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Researchers rebuild the brain's circuitry

Neuron transplants have repaired brain circuitry and substantially normalized function in mice with a brain disorder, an advance indicating that key areas of the mammalian brain are more reparable than was ...

Neuroscience created Nov 24, 2011 | popularity 4.6 / 5 (20) | comments 2 | with audio podcast

Brain circuits connected with memory discovered

(Medical Xpress) -- A new study published last week in Science reveals the discovery of a brain pathway that helps us link events that happen close together and play a role in memories.

Neuroscience created Nov 07, 2011 | popularity 4.7 / 5 (11) | comments 0 | with audio podcast report

Researchers link facial structure to kidney disease

(Medical Xpress)—Researchers at King's College London's Dental Institute have shown that people with a certain kind of kidney disease have characteristic facial features that may reflect the genetic mutation ...

Diseases, Conditions, Syndromes created Apr 24, 2013 | popularity 4 / 5 (1) | comments 1 | with audio podcast

Study discovers that stem cell senescence drives aging

Declining levels of the protein BubR1 occur when both people and animals age, and contribute to cell senescence or deterioration, weight loss, muscle wasting and cataracts. Mayo Clinic researchers have shown that adult progenitor ...

Medical research created Apr 18, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Study shows underlying connection between 'good' cholesterol and collagen in heart health

(Medical Xpress)—Arterial stiffening has long been considered a major risk factor for cardiovascular disease. Keeping arteries soft and supple might reduce disease risk, but the mechanisms of how arteries ...

Cardiology created Nov 01, 2012 | popularity 4 / 5 (3) | comments 0 | with audio podcast

Stay-at-home transcription factor prevents neurodegeneration

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow ...

Medical research created Oct 29, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Study uncovers mechanism by which tumor suppressor MIG6 triggers cell suicide

Death plays a big role in keeping things alive. Consider the tightly orchestrated suicide of cells—a phenomenon essential to everything from shaping an embryo to keeping it free of cancer later in life. ...

Cancer created Sep 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

Possible muscle disease therapeutic target found

The study of muscular system protein myostatin has been of great interest to researchers as a potential therapeutic target for people with muscular disorders. Although much is known about how myostatin affects muscle growth, ...

Medical research created Aug 06, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Mice with big brains provide insight into brain regeneration and developmental disorders

Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa (uOttawa) have discovered that mice that lack a gene called Snf2l have brains that are 35 per cent larger than normal. ...

Genetics created May 15, 2012 | popularity 3.5 / 5 (4) | comments 0 | with audio podcast

Researchers discover molecular basis of autistic symptoms in children with rare bone disorder

Children with multiple hereditary exostoses (MHE), an inherited genetic disease, suffer from multiple growths on their bones that cause pain and disfigurement. But beyond the physical symptoms of this condition, ...

Diseases, Conditions, Syndromes created Mar 12, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Blocking natural, marijuana-like chemical in the brain boosts fat burning

Stop exercising, eat as much as you want ... and still lose weight? It sounds impossible, but UC Irvine and Italian researchers have found that by blocking a natural, marijuana-like chemical regulating energy metabolism, ...

Medical research created Mar 06, 2012 | popularity 4.8 / 5 (6) | comments 9 | with audio podcast