HIV antibodies that are worth the wait
An effective vaccine against HIV-1 remains elusive, but one promising strategy focuses on designer antibodies that have much broader potency than most normal, exquisitely specific antibodies. These broadly ...
HIV & AIDS
Mar 28, 2013 |
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Scientists find potential loophole in pancreatic cancer defenses
Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control ...
Cancer
Mar 27, 2013 |
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New DNA sequences hone in on breast, ovarian cancer risk
Researchers at Mayo Clinic Cancer Center have identified new DNA sequences associated with breast cancer—the most common cancer among women, with an average risk of developing the disease of 10 percent—and ovarian cancer, ...
Cancer
Mar 27, 2013 |
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Novel gene drives development of different types of ovarian cancer
Researchers at Mayo Clinic Cancer Center have identified a novel gene that can contribute to a woman's susceptibility for developing ovarian cancer. Researchers identified the gene, called HNF1B, through large-scale analysis ...
Cancer
Mar 27, 2013 |
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Five genetic variations increase risk of ovarian cancer
An international research collaboration has found five new regions of the human genome that are linked to increased risks for developing ovarian cancer. Duke Medicine researchers played a leading role analyzing genetic information ...
Cancer
Mar 27, 2013 |
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Scientists find new gene markers for cancer risk
A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person's risk for breast, ovarian ...
Genetics
Mar 27, 2013 |
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Researchers decode biology of blood and iron disorders mapping out novel future therapies
Two studies led by investigators at Weill Cornell Medical College shed light on the molecular biology of three blood disorders, leading to novel strategies to treat these diseases.
Medical research
Mar 25, 2013 |
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Exploring the cause of sudden unexplained death in epilepsy
Dravet syndrome (DS) is a form of infantile-onset, treatment-resistant epilepsy that is caused by a mutation in the gene encoding a voltage-gated sodium channel, SCN1A. DS patients have a 30-fold increased risk of dying from ...
Medical research
Mar 25, 2013 |
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Learning from Lassa virus: Researchers discover gene mutations that can result in a congenital disorder
(Medical Xpress)—Researchers have known that two seemingly distant human maladies—a devastating set of hereditary disorders called Walker-Warburg syndrome and infection with the virus that causes hemorrhagic ...
Medical research
Mar 22, 2013 |
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New technology is key to better epilepsy treatment
(Medical Xpress)—University of Adelaide scientists are making a major impact on the understanding and diagnosis of epilepsy, which will lead to individualised treatments for sufferers.
Neuroscience
Mar 22, 2013 |
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Harnessing immune cells' adaptability to design an effective HIV vaccine
In infected individuals, HIV mutates rapidly to escape recognition by immune cells. This process of continuous evolution is the main obstacle to natural immunity and the development of an effective vaccine. A new study published ...
Immunology
Mar 21, 2013 |
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Genetic risk strategies needed for young, black, female breast cancer patients, study shows
Researchers at Moffitt Cancer Center and colleagues in Canada have published study results focused on black women younger than 50, a population disproportionately afflicted with and dying from early-onset breast cancer compared ...
Cancer
Mar 21, 2013 |
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Clues point to cause of a rare fat-distribution disease
Studying a protein that gives structure to the nucleus of cells, Johns Hopkins researchers stumbled upon mutations associated with familial partial lipodystrophy (FPLD), a rare disease that disrupts normal patterns of fat ...
Medical research
Mar 20, 2013 |
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When timing is everything: Research says beneficial mutations need specific circumstances to win out
When it comes to the sort of beneficial mutations that drive natural selection, there's new evidence that, evolutionarily speaking, timing is everything.
Genetics
Mar 20, 2013 |
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Researchers link cancer to failures in chromosome protection for the first time
A study published today in the journal Nature Genetics explores a new mechanism that may contribute to the development of several tumours, including Chronic Lymphocytic Leukaemia, a type of cancer that affects more than a ...
Genetics
Mar 19, 2013 |
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