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Naloxone

Naloxone is an opioid antagonist drug developed by Sankyo in the 1960s. Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. Naloxone is specifically used to counteract life-threatening depression of the central nervous system and respiratory system. Naloxone is also experimentally used in the treatment for congenital insensitivity to pain with anhidrosis (CIPA), an extremely rare disorder (1 in 125 million) that renders one unable to feel pain. It is marketed under various trademarks including Narcan, Nalone, and Narcanti, and has sometimes been mistakenly called "naltrexate." It is not to be confused with naltrexone, an opioid receptor antagonist with qualitatively different effects, used for dependence treatment rather than emergency overdose treatment.

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Estonia tops EU drug overdose deaths list

Officials in Estonia raised the alarm Wednesday after a report into drug use in Europe found that the small Baltic nation had the highest incidence of deaths from drug overdoses in the EU.

Medications created Feb 13, 2013 | popularity not rated yet | comments 0

Training bystanders to spot drug overdoses can reduce deaths

Training bystanders to recognize and respond to drug overdoses can significantly reduce the number of fatalities, finds a study published in BMJ today.

Health created Jan 31, 2013 | popularity not rated yet | comments 0

Study shows naloxone kits cost-effective in preventing overdose deaths

(Medical Xpress)—Giving heroin users kits with the overdose antidote naloxone is a cost-effective way to prevent overdose deaths and save lives, according to a study released this week in The Annals of ...

Medications created Jan 02, 2013 | popularity not rated yet | comments 0 | with audio podcast

Opioid overdose rates 'impossible' to ignore

(Medical Xpress)—Opioid over­dose now kills more people than both AIDS and homi­cides in America and has sur­passed auto­mo­bile acci­dents as the leading cause of acci­dental death in many states. According to the ...

Medications created Nov 21, 2012 | popularity 3.5 / 5 (2) | comments 0

Scientists can now block heroin, morphine addiction; clinical trials possible within 18 months

In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.

Neuroscience created Aug 14, 2012 | popularity 4.9 / 5 (30) | comments 8 | with audio podcast

'Substantial variation' in stocks of essential antidotes at UK hospitals

There is "substantial variation" in the stocks of essential antidotes used to treat various types of life threatening poisoning incidents in UK acute hospitals, finds research published online in Emergency Medicine Journal.

Other created Aug 08, 2012 | popularity not rated yet | comments 0

Pain relief through distraction -- it's not all in your head

Mental distractions make pain easier to take, and those pain-relieving effects aren't just in your head, according to a report published online on May 17 in Current Biology.

Medical research created May 17, 2012 | popularity 5 / 5 (2) | comments 2 | with audio podcast

Drug-overdose antidote is put in addicts' hands

(AP) -- Steve Wohlen lay on his front lawn, blue, unconscious and barely breathing, overdosing on heroin.

Addiction created Apr 26, 2012 | popularity not rated yet | comments 0

Suboxone is most effective in treating painkiller addiction

Individuals addicted to prescription painkillers are more likely to succeed in treatment with the aid of the medication buprenorphine-naloxone (Suboxone), report McLean Hospital and Harvard Medical School researchers in today's ...

Medications created Nov 07, 2011 | popularity not rated yet | comments 1

Researchers find anti-depressants reduce pain in opioid-dependent patients

In what is believed to be the first study of its kind to demonstrate an association between the antidepressant escitalopram and improved general pain, researchers from Boston University School of Medicine (BUSM), have found ...

Medical research created Nov 03, 2011 | popularity 5 / 5 (1) | comments 0