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Naloxone

Naloxone is an opioid antagonist drug developed by Sankyo in the 1960s. Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. Naloxone is specifically used to counteract life-threatening depression of the central nervous system and respiratory system. Naloxone is also experimentally used in the treatment for congenital insensitivity to pain with anhidrosis (CIPA), an extremely rare disorder (1 in 125 million) that renders one unable to feel pain. It is marketed under various trademarks including Narcan, Nalone, and Narcanti, and has sometimes been mistakenly called "naltrexate." It is not to be confused with naltrexone, an opioid receptor antagonist with qualitatively different effects, used for dependence treatment rather than emergency overdose treatment.

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Scientists can now block heroin, morphine addiction; clinical trials possible within 18 months

In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.

Neuroscience created Aug 14, 2012 | popularity 4.9 / 5 (30) | comments 8 | with audio podcast

Pain relief through distraction -- it's not all in your head

Mental distractions make pain easier to take, and those pain-relieving effects aren't just in your head, according to a report published online on May 17 in Current Biology.

Medical research created May 17, 2012 | popularity 5 / 5 (2) | comments 2 | with audio podcast

Opioid overdose rates 'impossible' to ignore

(Medical Xpress)—Opioid over­dose now kills more people than both AIDS and homi­cides in America and has sur­passed auto­mo­bile acci­dents as the leading cause of acci­dental death in many states. According to the ...

Medications created Nov 21, 2012 | popularity 3.5 / 5 (2) | comments 0

Researchers find anti-depressants reduce pain in opioid-dependent patients

In what is believed to be the first study of its kind to demonstrate an association between the antidepressant escitalopram and improved general pain, researchers from Boston University School of Medicine (BUSM), have found ...

Medical research created Nov 03, 2011 | popularity 5 / 5 (1) | comments 0