In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.
Aug 14, 2012
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The highest ever number of opioid-related overdose deaths in the United States was recorded in 2020 at 68,630, a 68% increase in just two years. Naloxone is a medicine that can rapidly reverse an opioid overdose, but a new ...
Sep 28, 2023
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There's been a recent push in the U.S. to make naloxone—a fast-acting opioid antidote—available without a prescription. This medication has saved lives, but it's less effective against powerful synthetic opioids, such ...
Mar 28, 2023
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The cost of buying the opioid antidote naloxone is out of reach for many uninsured Americans, a hurdle that may keep the treatment from saving more people who overdose on opioids, according to a new RAND Corporation study.
Aug 19, 2022
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A data-driven simulation model designed to help policymakers to better understand and address the nation's rampant opioid crisis has been developed by a team of scientists at Massachusetts General Hospital (MGH).
May 31, 2022
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Overdose deaths continue to be a national tragedy. More than 800,000 Americans died from an overdose between 1999–2019, and the annual rate of overdoses has increased dramatically during the pandemic, according to the latest ...
Apr 11, 2022
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Even though fentanyl-linked fatal overdoses are soaring among young adults, a new survey of American college students found that just 1 in 7 knew how to administer the overdose antidote drug naloxone.
Apr 22, 2024
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Nasal-administered naloxone is more cost-effective and could help reduce the number of opioid-related fatalities compared to the current publicly funded intermuscular version, a new study has found. The study, "An economic ...
Apr 8, 2024
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The White House on Wednesday launched a nationwide call for more training and better access to the lifesaving opioid overdose drug naloxone.
Mar 13, 2024
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An article published in the Canadian Medical Association Journal describes five things clinicians and harm reduction workers should know about xylazine, a veterinary medication adulterating the illicit opioid supply.
Feb 5, 2024
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Naloxone is an opioid antagonist drug developed by Sankyo in the 1960s. Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. Naloxone is specifically used to counteract life-threatening depression of the central nervous system and respiratory system. Naloxone is also experimentally used in the treatment for congenital insensitivity to pain with anhidrosis (CIPA), an extremely rare disorder (1 in 125 million) that renders one unable to feel pain. It is marketed under various trademarks including Narcan, Nalone, and Narcanti, and has sometimes been mistakenly called "naltrexate." It is not to be confused with naltrexone, an opioid receptor antagonist with qualitatively different effects, used for dependence treatment rather than emergency overdose treatment.
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