Green tea extract interferes with the formation of amyloid plaques in Alzheimer's disease
(Medical Xpress)—Researchers at the University of Michigan have found a new potential benefit of a molecule in green tea: preventing the misfolding of specific proteins in the brain.
Alzheimer's disease & dementia
Mar 05, 2013 |
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Two proteins offer a 'clearer' way to treat Huntington's disease
In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critic ...
Neuroscience
Jul 11, 2012 |
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Normal prion protein regulates iron metabolism
An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found.
Alzheimer's disease & dementia
Mar 13, 2013 |
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Neurons made from stem cells drive brain activity after transplantation in laboratory model
(Medical Xpress)—Researchers and patients look forward to the day when stem cells might be used to replace dying brain cells in Alzheimer's disease and other neurodegenerative conditions. Scientists are ...
Neuroscience
Nov 15, 2012 |
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Hunting neuron killers in Alzheimer's and traumatic brain injury
Levels of the protein appoptosin in the brain skyrocket in Alzheimer's disease and traumatic brain injury. Appoptosin is known for helping the body make heme, the molecule that carries iron in the blood. In a study published ...
Neuroscience
Nov 09, 2012 |
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Scientists block toxic protein that plays key role in Lou Gehrig's disease
October 28, 2012— Scientists at the Gladstone Institutes and the Stanford University School of Medicine have discovered how modifying a gene halts the toxic buildup of a protein found in nerve cells. These findings point ...
Medical research
Oct 28, 2012 |
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Developing stem cell model for Gaucher disease, neurodegenerative conditions
A new method of using adult stem cells as a model for the hereditary condition Gaucher disease could help accelerate the discovery of new, more effective therapies for this and other conditions such as Parkinson's, according ...
Neuroscience
Oct 15, 2012 |
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Study examines delayed, misdiagnosis of sporadic Jakob-Creutzfeldt disease
A medical record review study of 97 patients with the fatal, degenerative brain disorder sporadic Jakob-Creutzfeldt disease (sCJD) suggests that a correct diagnosis of the disease was often delayed by a variety of misdiagnoses, ...
Neuroscience
Sep 24, 2012 |
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Immune cell death safeguards against autoimmune disease
Researchers at the Walter and Eliza Hall Institute have discovered that a pair of molecules work together to kill so-called 'self-reactive' immune cells that are programmed to attack the body's own organs. ...
Immunology
Sep 06, 2012 |
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Rejected drug may protect against toxic substance common to Alzheimer's and Parkinson's diseases
The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative ...
Neuroscience
Aug 13, 2012 |
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Brain variants of protein associated with Huntington's and other neurodegenerative diseases identified
(Medical Xpress) -- A protein essential for metabolism and recently associated with neurodegenerative diseases also occurs in several brain-specific forms. This discovery emerged in the course of a research ...
Genetics
Jul 23, 2012 |
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Scientists discover gene which causes rare disease in babies
A rare disease which often first presents in newborn babies has been traced to a novel genetic defect, scientists at Queen Mary, University of London have found.
Genetics
May 29, 2012 |
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Observations refute widely held view on causal mechanism in amyotrophic lateral sclerosis
In science, refuting a hypothesis can be as significant as proving one, all the more so in research aimed at elucidating how diseases proceed with a view toward preventing, treating, or curing them. Such a ...
Diseases, Conditions, Syndromes
Feb 29, 2012 |
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Lithium profoundly prevents brain damage associated with Parkinson's disease
Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson's disease (PD) in a mouse model of the condition.
Parkinson's & Movement disorders
Jun 24, 2011 |
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Rare genetic disorder provides unique insight into Parkinson's disease
Massachusetts General Hospital investigators appear to have found the mechanism behind a previously reported link between the rare genetic condition Gaucher disease and the common neurodegenerative disorder Parkinson's disease. ...
Genetics
Jun 23, 2011 |
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