Neuroscience

Lessons learned from the adult neurogenesis debate

Since the 1960s, consensus about whether human adults generate new neurons with age has swayed back and forth from "yes, at least in some places in the brain" to "no, not at all." The debate reignited in 2018 when two headline-grabbing ...

Medical research

New insight into the generation of new neurons in the adult brain

Researchers at Sahlgrenska Academy at the University of Gothenburg, Sweden, in collaboration with research groups in Finland, Canada and Slovenia, have discovered a novel and unexpected function of nestin, the best-known ...

Neuroscience

Neurons migrate in the nascent brain as if on rails

Researchers examined the brain development of mouse embryos. They concentrated on a pool of neuronal precursor cells that develops in the hindbrain about ten days after fertilization. These mature into nerve cells and then ...

Neuroscience

New gene therapy reprograms brain glial cells into neurons

A new gene therapy can turn certain brain glial cells into functioning neurons, which in turn could help repair the brain after a stroke or during neurological disorders like Alzheimer's or Parkinson's diseases.

Neuroscience

How clutch molecules enable neuron migration

The brain can discriminate over 1 trillion odors. Once entering the nose, odor-related molecules activate olfactory neurons. Neuron signals first accumulate at the olfactory bulb before being passed on to activate the appropriate ...

Neuroscience

Early environment may shape axon pathfinding

A new mechanism regulating the early development of connections between the two sides of the nervous system has been identified in a paper published in eNeuro. The work demonstrates that neuronal activity is required for ...

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