News tagged with nitric oxide

Related topics: high blood pressure , blood vessels

'Moonlighting' enzyme unravels arginine paradox

(Medical Xpress) -- Nearly 20 years ago, the journal Science tagged nitric oxide as the "molecule of the year." Since that time, researchers have tried to study and target this simple molecule that is involved in virtually every ...

Nov 13, 2011
popularity 5 / 5 (3) | comments 2 | with audio podcast

Heart attack research discovers new treatment target

Research led by David Lefer, PhD, Professor and Director of the Cardiovascular Center of Excellence at LSU Health Sciences Center New Orleans School of Medicine, demonstrates for the first time cross-talk between two protective ...

Feb 10, 2014
popularity 5 / 5 (3) | comments 0 | with audio podcast

Nitric oxide

Nitric oxide or nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals, including humans, and is an extremely important intermediate in the chemical industry. It is also an air pollutant produced by cigarette smoke, automobile engines and power plants.

NO is an important messenger molecule involved in many physiological and pathological processes within the mammalian body both beneficial and detrimental. Appropriate levels of NO production are important in protecting an organ such as the liver from ischemic damage. However sustained levels of NO production result in direct tissue toxicity and contribute to the vascular collapse associated with septic shock, whereas chronic expression of NO is associated with various carcinomas and inflammatory conditions including juvenile diabetes, multiple sclerosis, arthritis and ulcerative colitis.

Nitric oxide should not be confused with nitrous oxide (N2O), a general anaesthetic and greenhouse gas, or with nitrogen dioxide (NO2) which is another air pollutant. The nitric oxide molecule is a free radical, which is relevant to understanding its high reactivity.

Despite being a simple molecule, NO is a fundamental player in the fields of neuroscience, physiology, and immunology, and was proclaimed “Molecule of the Year” in 1992.

This text uses material from Wikipedia licensed under CC BY-SA