Study in mice shows blocking abnormal stem cell signal during aging lessens related bone loss
A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.
Sep 27, 2023
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A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.
Sep 27, 2023
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Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, ...
Jan 5, 2023
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When a muscle grows, because its owner is still growing too or has started exercising regularly, some of the stem cells in this muscle develop into new muscle cells. The same thing happens when an injured muscle starts to ...
Feb 26, 2021
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When a muscle grows or a muscle injury heals, some stem cells develop into new muscle cells. A research team at the MDC led by Carmen Birchmeier has now described in the journal Genes & Development how this process is regulated ...
Mar 18, 2019
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Hematopoietic stem cells (HSCs) give rise to all other blood cell types, but their development and how their fate is determined has long remained a mystery. In a paper published online this week in Nature, researchers at ...
Aug 14, 2014
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Nature is thrifty. The same signals that embryonic cells use to decide whether to become nerves, skin or bone come into play again when adult animals are learning whether to become afraid.
Aug 7, 2014
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A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive ...
Apr 1, 2013
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Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders.
Mar 1, 2013
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A new study led by researchers at Hospital for Special Surgery identifies the mechanism by which a cell signaling pathway contributes to the development of rheumatoid arthritis (RA). In addition, the study provides evidence ...
May 20, 2012
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Sleeping worms have much to teach people, a notion famously applied by the children's show "Sesame Street," in which Oscar the Grouch often reads bedtime stories to his pet worm Slimy. Based on research with their own worms, ...
May 5, 2011
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