News tagged with nuclear genes

Scientists find clues to some inherited heart diseases

(Medical Xpress)—Cornell researchers have uncovered the basic cell biology that helps explain heart defects found in diseases known as laminopathies, a group of some 15 genetic disorders that include forms ...

Medical research May 07, 2013 | 5 / 5 (2) | 0 |

Molecule's structure reveals new therapeutic opportunities for rare diabetes

Researchers at Sanford-Burnham Medical Research Institute have determined the complete three-dimensional structure of a protein called HNF-4α. HNF-4α controls gene expression in the liver and pancreas, ...

Medical research Mar 13, 2013 | 5 / 5 (3) | 0 |

Scientists create one-step gene test for mitochondrial diseases

More powerful gene-sequencing tools have increasingly been uncovering disease secrets in DNA within the cell nucleus. Now a research team is expanding those rapid next-generation sequencing tests to analyze a separate source ...

Medical research Jan 29, 2013 | not rated yet | 0 |

Personal epigenetic 'signatures' found consistent in prostate cancer patients' metastases

In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient. The discovery of the ...

Cancer Jan 23, 2013 | not rated yet | 0 |

Researchers use stem cells to show connection between neural cell disruption and Parkinson's disease

(Medical Xpress)—A diverse team of biologists has shown using induced pluripotent stem cells (iPSCs) that a gene mutation that causes malformations in the structure of the nuclear envelope of neural cells, ...

Parkinson's & Movement disorders Oct 18, 2012 | 5 / 5 (2) | 0 |

Gene variant linked with reduced lung cancer risk

A variant in a gene involved with inflammation and the immune response is linked with a decreased risk of lung cancer. That is the finding of an analysis published early online in Cancer, a peer-reviewed journal of the Am ...

Cancer Oct 08, 2012 | not rated yet | 0

Research finds key molecules involved in forming long-term memories

How does one's experience of an event get translated into a memory that can be accessed months, even years later? A team led by University of Pennsylvania scientists has come closer to answering that question, identifying ...

Medical research Sep 10, 2012 | 5 / 5 (6) | 3 |

Researchers make promising discovery in pursuit of effective lymphoma treatments

Researchers at NYU School of Medicine have identified a target for slowing the progression of multiple myeloma by using currently available drugs.

Cancer May 16, 2012 | 5 / 5 (1) | 0 |

PET technique promises better detection and response assessment for Non-Hodgkin's lymphoma

Positron emission tomography (PET) and a molecular imaging agent that captures the proliferation of cancer cells could prove to be a valuable method for imaging a form of Non-Hodgkin's disease called mantle cell lymphoma, ...

Cancer Dec 21, 2011 | not rated yet | 0

Scientists describe mechanism for rare muscle disease

(Medical Xpress) -- A team of scientists from the Friedrich Miescher Institute for Biomedical Research and the Hebrew University of Jerusalem describe in C. elegans the process leading to a rare form of Emery-Dreifuss ...

Medical research Oct 03, 2011 | not rated yet | 0 |

In next-gen DNA sequence, new answers to a rare and devastating disease

In Leigh syndrome, infants are born apparently healthy only to develop movement and breathing disorders that worsen over time, often leading to death by the age of 3. The problem is that the mitochondria responsible for powering ...

Medical research Sep 06, 2011 | 5 / 5 (2) | 0 |

PGD can permit the birth of healthy children to women carrying mitochondrial DNA disease

Pre-implantation genetic diagnosis (PGD) can give women at risk of passing on a mitochondrial DNA disorder to their offspring a good chance of being able to give birth to an unaffected child, a researcher told the annual ...

Genetics May 30, 2011 | not rated yet | 0 |

Mothers curse linked to male infertility

(Medical Xpress) -- Researchers have discovered the first real evidence of the 'mother's curse' and its connection to male infertility due to genetic mutations in mitochondria. Led by Dr. Damian Dowling from Monash University ...

Genetics May 16, 2011 | 3.7 / 5 (3) | 0 |

Scientists create new genetic model of premature aging diseases

Working with a group of national and international researchers, scientists from the Florida campus of The Scripps Research Institute have developed a new genetic model of premature aging disorders that could shed light on ...

Genetics Apr 29, 2011 | 5 / 5 (1) | 0 |