News tagged with nuclear magnetic resonance
New data from two clinical trials presented today at the International Liver Congress 2013 demonstrate substantial improvements in the detection of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) using diagnostic ...
Cancer Apr 26, 2013 | not rated yet | 0
Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have provided important new details into the activation of the epidermal growth factor ...
Cancer Feb 11, 2013 | 5 / 5 (3) | 0 |
Metabolomics key to identifying disease pathway: Research reveals lactic acid's role in lung disease
(Medical Xpress)—Expertise at Pacific Northwest National Laboratory contributed to the understanding of the role of cellular metabolism in the pathogenesis of a currently untreatable lung disease. This ...
Diseases, Conditions, Syndromes Jan 14, 2013 | not rated yet | 0 |
Researchers have found a novel, non-invasive technique for measuring brain hot spots caused by electromagnetic radiation from mobile phones, according to a study published today.
Medical research Dec 17, 2012 | 3.3 / 5 (10) | 9 |
(Medical Xpress)—Research by University of Notre Dame biochemist Anthony S. Serianni is providing new insights that could have important implications for understanding and treating diabetes.
Diabetes Dec 11, 2012 | 5 / 5 (1) | 0 |
A team of scientists from the Spanish National Cancer Research Centre, led by its director, María Blasco, together with Jose M. Mato, the director of the Center for Cooperative Research in Biosciences, has shown that the ...
Medical research Dec 04, 2012 | not rated yet | 0
A novel miniature diagnostic platform using nuclear magnetic resonance (NMR) technology is capable of detecting minuscule cell particles known as microvesicles in a drop of blood. Microvesicles shed by cancer ...
Medical research Nov 11, 2012 | 5 / 5 (1) | 0 |
Using solid-state nuclear magnetic resonance (NMR) spectroscopy, researchers at Luleå University of Technology in collaboration with Warwick University in the UK for the first time in the world managed to ...
Alzheimer's disease & dementia Nov 05, 2012 | not rated yet | 0
Groundbreaking research taking place at the University of York could lead to Alzheimer's disease being diagnosed in minutes using a simple brain scan.
Alzheimer's disease & dementia Oct 08, 2012 | 5 / 5 (1) | 1
The use of diagnostic imaging in Medicare patients with stage IV cancer has increased faster than among those with early-stage (stages I and II) disease, according to a study published July 30 in the Journal of the National Ca ...
Cancer Jul 30, 2012 | not rated yet | 0
Investigators at the Center for Structural Genomics of Infectious Diseases (CSGID) and the Seattle Structural Genomics Center for Infectious Disease (SSGCID) announced today that they reached a significant milestone by determining ...
Diseases, Conditions, Syndromes Jun 05, 2012 | not rated yet | 0
Imaging amino acid transporters with positron emission tomography/computed tomography (PET/CT) has been shown to significantly alter intended management plans for patients with brain tumors, according to research in the March ...
Cancer Mar 01, 2012 | not rated yet | 0
(Medical Xpress) -- The multidrug transporter EmrE functions as an asymmetric antiparallel dimer (molecule with two subunits). Drug (blue) transport from the inside to the outside of the cell membrane is accomplished ...
Medical research Jan 31, 2012 | not rated yet | 0 |
Genetic regulation of metabolomic biomarkers -- paths to cardiovascular diseases and type 2 diabetes
In a study to the genetic variance of human metabolism, researchers have identified thirty one regions of the genome that were associated with levels of circulating metabolites, i.e., small molecules that ...
Diabetes Jan 29, 2012 | not rated yet | 0
Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 ...
Medical research Jan 09, 2012 | 5 / 5 (2) | 0 |
Nuclear magnetic resonance
Nuclear magnetic resonance (NMR) is a property that magnetic nuclei have in a magnetic field and applied electromagnetic (EM) pulse, which cause the nuclei to absorb energy from the EM pulse and radiate this energy back out. The energy radiated back out is at a specific resonance frequency which depends on the strength of the magnetic field and other factors. This allows the observation of specific quantum mechanical magnetic properties of an atomic nucleus. Many scientific techniques exploit NMR phenomena to study molecular physics, crystals and non-crystalline materials through NMR spectroscopy. NMR is also routinely used in advanced medical imaging techniques, such as in magnetic resonance imaging (MRI).
All nuclei that contain odd numbers of nucleons have an intrinsic magnetic moment and angular momentum, in other words a spin > 0. The most commonly studied nuclei are 1H (the most NMR-sensitive isotope after the radioactive 3H) and 13C, although nuclei from isotopes of many other elements (e.g. 2H, 10B, 11B, 14N, 15N, 17O, 19F, 23Na, 29Si, 31P, 35Cl, 113Cd, 195Pt) are studied by high-field NMR spectroscopy as well.
A key feature of NMR is that the resonance frequency of a particular substance is directly proportional to the strength of the applied magnetic field. It is this feature that is exploited in imaging techniques; if a sample is placed in a non-uniform magnetic field then the resonance frequencies of the sample's nuclei depend on where in the field they are located. Since the resolution of the imaging techniques depends on how big the gradient of the field is, many efforts are made to develop more powerful magnets, often using superconductors. The effectiveness of NMR can also be improved using hyperpolarization, and/or using two-dimensional, three-dimensional and higher dimension multi-frequency techniques.
The principle of NMR usually involves two sequential steps:
The two fields are usually chosen to be perpendicular to each other as this maximises the NMR signal strength. The resulting response by the total magnetization (M) of the nuclear spins is the phenomenon that is exploited in NMR spectroscopy and magnetic resonance imaging. Both use intense applied magnetic fields (H0) in order to achieve dispersion and very high stability to deliver spectral resolution, the details of which are described by chemical shifts, the Zeeman effect, and Knight shifts (in metals).
NMR phenomena are also utilized in low-field NMR, NMR spectroscopy and MRI in the Earth's magnetic field (referred to as Earth's field NMR), and in several types of magnetometers.
For more information about Nuclear magnetic resonance, read the full article at
This text uses material from Wikipedia and is available under the GNU Free Documentation License.