Diseases, Conditions, Syndromes

New research insights hold promise for kids with DMD

Prednisone, the current standard of care used to treat kids with Duchenne muscular dystrophy (DMD), reduces chronic inflammation but has harsh side effects. Eplerenone, a heart failure drug, is used in older patients to treat ...

Neuroscience

Rat hippocampal neurons: An executor of neuroinflammation

Recent findings suggest that Toll-like receptor 4 expressed in the central nervous system, especially in glial cells, plays a vital role in neuroinflammation and neurodegenerative conditions. Traditional theory suggests that ...

Diseases, Conditions, Syndromes

UCLA-led team may have found key to cause of Cushing disease

Cushing disease is a life-threatening disorder most commonly triggered by tumors, often benign, in the pituitary glands, resulting in excess production of adrenocorticotrophic hormone (ACTH). The condition is marked by progressive ...

Oncology & Cancer

New details on the molecular machinery of cancer

Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have provided important new details into the activation of the epidermal growth factor receptor (EGFR), ...

Medical research

Scientists discover 'back door' of nuclear receptor

On Monday 7 December the journal Nature Communications published the research findings of TU/e, Merck Research Laboratories and Leiden University concerning an entirely new way of antagonizing a human nuclear receptor. The ...

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